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Merck

W255602

Sigma-Aldrich

γ-Hexalactone

≥98%, FCC, FG

Sinónimos:

γ-Caprolactone, γ-Ethyl-γ-butyrolactone

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About This Item

Fórmula empírica (notación de Hill):
C6H10O2
Número de CAS:
Peso molecular:
114.14
FEMA Number:
2556
Beilstein/REAXYS Number:
6114822
EC Number:
Council of Europe no.:
2254
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
10.021
NACRES:
NA.21

biological source

synthetic

Quality Level

grade

FG
Fragrance grade
Halal
Kosher

agency

follows IFRA guidelines
meets purity specifications of JECFA

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FCC
FDA 21 CFR 117
FDA 21 CFR 172.515

assay

≥98%

refractive index

n20/D 1.439 (lit.)

bp

219 °C (lit.)

density

1.023 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

organoleptic

coconut; coumarin; creamy; sweet

SMILES string

CCC1CCC(=O)O1

InChI

1S/C6H10O2/c1-2-5-3-4-6(7)8-5/h5H,2-4H2,1H3

InChI key

JBFHTYHTHYHCDJ-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544)

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Categorías relacionadas

Application


  • RIFM fragrance ingredient safety assessment, γ-hexalactone, CAS Registry Number 695-06-7.: This article provides a comprehensive safety assessment of γ-Hexalactone, a key fragrance ingredient, supporting its safe use under current practices and concentration levels in consumer products (Api et al., 2022).

  • Production of Hydroxy Fatty Acids, Precursors of γ-Hexalactone, Contributes to the Characteristic Sweet Aroma of Beef.: This study highlights the biochemical pathways involved in the formation of γ-Hexalactone through the production of hydroxy fatty acids, significantly impacting the flavor profile of beef (Ueda et al., 2022).

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

208.4 °F - closed cup

flash_point_c

98 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


Certificados de análisis (COA)

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Olga Khersonsky et al.
Biochemistry, 44(16), 6371-6382 (2005-04-20)
PON1 is the best-studied member of a family of enzymes called serum paraoxonases, or PONs, identified in mammals (including humans) and other vertebrates as well as in invertebrates. PONs exhibit a range of important activities, including drug metabolism and detoxification
H Thoma et al.
Journal of chromatography, 309(1), 17-32 (1984-07-13)
A two-step ultrafiltration method combined with anion-exchange chromatography is described for the separation of lipophilic and strongly lipophobic acids occurring in human blood, serum and plasma. After treatment with diazomethane, the acid fractions are separated further by gas chromatography. The
Profile of volatile metabolites in human urine.
A Zlatkis et al.
Clinical chemistry, 17(7), 592-594 (1971-07-01)
Laura E Korhonen et al.
Journal of medicinal chemistry, 48(11), 3808-3815 (2005-05-27)
The purpose of this study was to determine the cytochrome P450 1A2 (CYP1A2) inhibition potencies of structurally diverse compounds to create a comprehensive three-dimensional quantitative structure-activity relationship (3D-QSAR) model of CYP1A2 inhibitors and to use this model to predict the

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