This product is an M-Clarity level 100 item. The method of preparation is considered proprietary.
739960
Resomer® RG 505, Poly(D,L-lactide-co-glycolide)
ester terminated, Mw 54,000-69,000
Sinónimos:
PLGA
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$72.200
5 G
$234.000
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1 G
$72.200
5 G
$234.000
About This Item
Fórmula lineal:
[C3H4O2]x[C2H2O2]y
Número de CAS:
Número MDL:
Código UNSPSC:
12162002
NACRES:
NA.23
Productos recomendados
Nivel de calidad
Formulario
amorphous
cociente alimentación
lactide:glycolide 50:50
mol peso
Mw 54,000-69,000
marco temporal de la degradación
<3 months
viscosidad
0.61-0.74 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)
temperatura de transición
Tg 48-52 °C
temp. de almacenamiento
2-8°C
cadena SMILES
O2C(C(=O)OC(C2=O)C)C.O1CC(=O)OCC1=O
InChI
1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2
Clave InChI
LCSKNASZPVZHEG-UHFFFAOYSA-N
Categorías relacionadas
Descripción general
Poly(lactide-co-glycolide)(PLGA) is a biodegradable polymer used in the preparation of polymericmicrospheres. These polymers degrade in vivo by hydrolysis of their esterbackbone into non-toxic products, which are excreted by the kidneys oreliminated as CO2 and water through biochemical pathways. PLGAmicrospheres have been widely used to encapsulate drug molecules and have beenused as long-acting, sustained-release pharmaceutical formulations.
Aplicación
Poly(lactide-co-glycolide)(PLGA) can be used to fabricate sustained-release drug delivery systems, for example, it can be used to encapsulate the anti-inflammatory lipophilic drug atorvastatin.
Información legal
Product of Evonik
RESOMER is a registered trademark of Evonik Rohm GmbH
Código de clase de almacenamiento
11 - Combustible Solids
Clase de riesgo para el agua (WGK)
WGK 3
Punto de inflamabilidad (°F)
Not applicable
Punto de inflamabilidad (°C)
Not applicable
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