L-Threoninol also known as (2R,3R)-2-Amino-1,3-butanediol, is an amino alcohol, which is commonly used in solution phase peptide synthesis.
Application
L-Threoninol can be used as artificial abasic nucleoside in the synthesis and modification of oligodeoxynucleotide and can also be utilized to synthesize pyrene-L-threoninyl analogues. [1][2]
Potent triple helix stabilization by 5?, 3?-modified triplex-forming oligonucleotides
N Ben Gaied
Chembiochem, 10, 1839-1851 (2009)
Synthesis and properties of an oligonucleotide modified with an acridine derivative at the artificial abasic site
K Fukui
Bioconjugate Chemistry, 7, 349-355 (1996)
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