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Ascentis® Express 90Å C8 (2.7 μm) HPLC Columns

L × I.D. 7.5 cm × 4.6 mm, HPLC Column

Sinonimo/i:

Core-shell (SPP) Fused Core C8 HPLC column

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About This Item

Codice UNSPSC:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Colonna HPLC Ascentis® Express C8, 2,7 μm, 2.7 μm particle size, L × I.D. 7.5 cm × 4.6 mm

Materiali

stainless steel column

agenzia

suitable for USP L7

Nome Commerciale

Ascentis®

Caratteristiche

endcapped

Produttore/marchio commerciale

Ascentis®

Confezionamento

1 ea of

Parametri

60 °C temp. range
600 bar max. pressure (9000 psi)

tecniche

HPLC: suitable
LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable

Lungh. × D.I.

7.5 cm × 4.6 mm

Area superficiale

135 m2/g

Impurezze

<5 ppm metals

Matrice

Fused-Core particle platform
superficially porous particle

Gruppo funzionale matrice

C8 (octyl) phase

Dimensione particelle

2.7 μm

Dimensione pori

90 Å

operating pH range

2-9

applicazioni

food and beverages

Tecnica di separazione

reversed phase

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Descrizione generale

Colonne HPLC Ascentis Express, attraverso l′uso della tecnologia di particelle Fused-Core® offrono l′alta velocità ed efficienza delle particelle sotto 2 μm nel contempo mantenendo contropressioni più basse. La combinazione di alta efficienza e bassa contropressione porta vantaggi agli utenti di UPLC® (o altri sistemi UHPLC a pressione ultra-alta), nonché agli utenti di HPLC convenzionali.
Andare alla pagina Ascentis Express per ulteriori informazioni sulla nuova zecnologia presente in questa colonna.

Applicazioni


  • Recent trends in ultra-fast HPLC: new generation superficially porous silica columns.: This review explores the evolution and performance of superficially porous silica columns in high-performance liquid chromatography (HPLC), including those similar to the Ascentis Express C8, 2.7 μm. The focus is on the technology′s impact on enhancing analytical speed and efficiency (Ali et al., 2012).

  • Development and validation of an HPLC-MS/MS method to determine clopidogrel in human plasma. Use of incurred samples to test back-conversion.: This study details the development of an HPLC-MS/MS analytical method using columns such as the Ascentis Express C8, 2.7 μm, aimed at quantifying clopidogrel in plasma, demonstrating the column′s utility in clinical pharmacokinetic assessments (Silvestro et al., 2010).

Note legali

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.
UPLC is a registered trademark of Waters

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Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
USGT001762
USGT001761
USGT001760
USGT001759
USGT001758

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Ugandar Reddy Inugala et al.
Journal of chromatographic science, 51(5), 453-459 (2012-10-13)
This paper describes the development of a rapid, novel, stability-indicating gradient reversed-phase high-performance liquid chromatographic method and associated system suitability parameters for the analysis of naproxcinod in the presence of its related substances and degradents using a quality-by-design approach. All
Sreenivasa Rao Chitturi et al.
Journal of pharmaceutical and biomedical analysis, 55(1), 31-47 (2011-02-15)
This paper proposes a simple and selective RP-HPLC method for the determination of process impurities and degradation products (degradants) of atazanavir sulfate (ATV) drug substance. Chromatographic separation was achieved on Ascentis(®) Express C8, (150mm×4.6mm, 2.7μm) column thermostated at 30°C under
Luigi Silvestro et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(30), 3134-3142 (2010-10-20)
Quantitative methods using LC-MS/MS allow achievement of adequate sensitivity for pharmacokinetic studies with clopidogrel; three such methods, with LLOQs as low as 5 pg/mL, were developed and fully validated according to the well established FDA 2001 guidelines. The chromatographic separations
Han Young Eom et al.
Journal of chromatography. A, 1217(26), 4347-4354 (2010-05-11)
Saikosaponins are triterpene saponins derived from the roots of Bupleurum falcatum L. (Umbelliferae), which has been traditionally used to treat fever, inflammation, liver diseases, and nephritis. It is difficult to analyze saikosaponins using HPLC-UV due to the lack of chromophores.
Federica Pellati et al.
Journal of pharmaceutical and biomedical analysis, 81-82, 126-132 (2013-05-07)
A closed-vessel microwave-assisted extraction (MAE) technique was optimized for the first time for the extraction of polyphenols from raw propolis. The results obtained by means of response surface experimental design methodology showed that the best global response was reached when
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Articoli

Ascentis® Express C8 U/HPLC Columns

When a C18 doesn′t give the desired separation, or your sample contains compounds that are known to be difficult to retain or resolve on a C18, consider changing to an Ascentis® Express C8 column.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.