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59354-U

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Discovery® C8 (5 µm) HPLC Columns

L × I.D. 25 cm × 4.6 mm, HPLC Column

Sinonimo/i:

C8 Reversed-Phase Chromatography Column

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About This Item

Codice UNSPSC:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Discovery® C8 HPLC Column, 5 μm particle size, L × I.D. 25 cm × 4.6 mm

Materiali

stainless steel column

agenzia

suitable for USP L7

Nome Commerciale

Discovery®

Caratteristiche

endcapped

Produttore/marchio commerciale

Discovery®

Confezionamento

1 ea of

Grado di funzionalizzazione

7.5% Carbon loading

Parametri

≤70 °C temp. range
400 bar pressure (5801 psi)

tecniche

HPLC: suitable
LC/MS: suitable

Lungh. × D.I.

25 cm × 4.6 mm

Area superficiale

200 m2/g

Copertura della superficie

3.4 μmol/m2

Impurezze

<10 ppm metals

Matrice

silica gel, high purity, spherical base material
fully porous particle

Gruppo funzionale matrice

C8 (octyl) phase

Dimensione particelle

5 μm

Dimensione pori

180 Å

operating pH range

2-8

applicazioni

food and beverages

Tecnica di separazione

reversed phase

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Categorie correlate

Applicazioni

Discovery® C8 HPLC column may be used in the determination of bisphenol A, genistein, bisphenol A β-D-glucuronide (BPA gluc), and genistein 4′-β-D-glucuronide (genistein gluc) in biological matrices including urine, cultures and tissues using solid-phase microextraction (SPME), followed by high-performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS).

Caratteristiche e vantaggi

  • Excellent reproducibility
  • Faster separation of strongly hydrophobic analytes than C18 columns
  • Stable, low-bleed LC-MS separations
  • Exceptional peak shapes for basic and acidic compounds
  • Compatible with low organic/highly aqueous mobile phases

Note legali

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificati d'analisi (COA)

Lot/Batch Number
292647-06
292647-05
292647-04
292647-03
292647-02

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Measurement of bisphenol A, bisphenol A β-d-glucuronide, genistein, and genistein 4′- β-d-glucuronide via SPE and HPLC-MS/MS.
Coughlin LJ, et al.
Analytical and Bioanalytical Chemistry, 401, 995-1002 (2011)
M Q Zhang et al.
Die Pharmazie, 46(10), 687-700 (1991-10-01)
The rapid growth in the quinolone research changed the whole face of the previous SAR concepts. So far structural modifications at all positions of the quinolone nucleus except the 4-oxo group have successfully lead to the discovery of potent antimicrobial
G L Bundy et al.
The Journal of biological chemistry, 261(2), 747-751 (1986-01-15)
The gorgonian coral Pseudoplexaura porosa contains a lipoxygenase capable of converting exogenous arachidonic acid into (8R)-8-hydroperoxy-5,9,11,14-eicosatetraenoic acid. The (8R)- (or 8-L-) configuration in this product, opposite to that observed in previously reported 8-lipoxygenase products, was determined unambiguously by comparison of
Hugo M Botelho et al.
Scientific reports, 5, 9038-9038 (2015-03-13)
Plasma membrane proteins are essential molecules in the cell which mediate interactions with the exterior milieu, thus representing key drug targets for present pharma. Not surprisingly, protein traffic disorders include a large range of diseases sharing the common mechanism of
Wai Shun Mak et al.
Nature communications, 6, 10005-10005 (2015-11-26)
The ability to biosynthetically produce chemicals beyond what is commonly found in Nature requires the discovery of novel enzyme function. Here we utilize two approaches to discover enzymes that enable specific production of longer-chain (C5-C8) alcohols from sugar. The first
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