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T3001

Sigma-Aldrich

(+)-α-Tocopherol acetate

oil or semi-solid, ~1360 IU/g

Sinonimo/i:

Vitamin E acetate

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About This Item

Formula empirica (notazione di Hill):
C31H52O3
Numero CAS:
58-95-7
Peso molecolare:
472.74
Numero CE:
200-405-4
Numero MDL:
MFCD00072052
Codice UNSPSC:
12352205
eCl@ss:
34058007
ID PubChem:
24900095
NACRES:
NA.79

Origine biologica

plant

Livello qualitativo

200

Descrizione

Synthesized from natural α-tocopherol

Forma fisica

oil or semi-solid

Attività specifica

~1360 IU/g

Colore

yellow

Punto di fusione

~25 °C (lit.)

Temperatura di conservazione

room temp

Stringa SMILE

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(OC(C)=O)c(C)c(C)c2O1

InChI

1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1
ZAKOWWREFLAJOT-CEFNRUSXSA-N

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Categorie correlate

Descrizione generale

α-Tocopherol acetate is a fat soluble vitamin and a form of vitamin E. It can be obtained through dietary sources. RRRα-Tocopherol is a natural form of α-tocopherol.

Applicazioni

(+)-α-Tocopherol acetate has been used:
  • as a component of growth medium for retinal cell lines
  • as an external standard in high performance liquid chromatography (HPLC) to study its composition in leafy vegetables
  • in the preparation of trans-resveratrol-encapsulated lipid nanocarriers (R-nano)

Azioni biochim/fisiol

α-Tocopherol is also known as a radical-chain breaker due to its anti-oxidant property.
Tocopherols (TCP) (vitamin E) are a series (α, β,γ and δ) of chiral organic molecules that vary in their degree of methylation of the phenol moiety of the chromanol ring. Tocopherols are lipid soluble anti-oxidants that protect cell membranes from oxidative damage. α-Tocopherol is the form of tocopherol preferentially absorbed by homo sapiens. Tocopherol acetate has properties similar but not identical to α-tocopherol.

Avvertenza

Does not air oxidize.

Indicazioni di pericolo

H413

Consigli di prudenza

P273 - P501

Classi di pericolo

Aquatic Chronic 4

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Dispositivi di protezione individuale

Eyeshields, Gloves

Certificati d'analisi (COA)

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Effects of natural (RRR α-tocopherol acetate) or synthetic (all-rac α-tocopherol acetate) vitamin E supplementation on reproductive efficiency in beef cows.
Horn M, Gunn P, Van Emon M, et al.
Journal of Animal Science, 88, 3121-3127 (2011)
Partial nutrient characterization of arugula (rocket-Eruca sativa L.) and the effect of heat treatment on its lipoxidase activity
Tassi EMM, et al.
Brazilian Journal of Food Technology, 21 (2018)
Safety assessment of the substance alpha-tocopherol acetate for use in food contact materials
Bolognesi C, et al.
EFSA Journal, 14(3), 4412-4412 (2016)
Resveratrol liposomes and lipid nanocarriers: comparison of characteristics and inducing browning of white adipocytes
Zu Y, et al.
Colloids and Surfaces. B, Biointerfaces, 164, 414-423 (2018)
P C Allen et al.
Poultry science, 81(1), 41-48 (2002-03-12)
In two trials, broiler chickens, processed similarly to those placed in commercial operation, were fed, from 1 d of age, a range (13 to 200 ppm) of DL-alpha-tocopheryl acetate (VE-AC) levels, and the effects on the pathology of Eimeria maxima
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Articoli

Vitamin E, Tocopherol, in Cell Culture

Importance and uses of vitamin E (tocopherol) in serum-free eukaryotic, including hybridoma and chinese hamster ovary (CHO), cell cultures.

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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