Passa al contenuto
Merck
Tutte le immagini(5)

Documenti fondamentali

Visualizza tutta la documentazione

G6013

Sigma-Aldrich

L-Glutathione reduced

≥98.0%, suitable for cell culture, BioReagent

Sinonimo/i:

Glutathione, Reduced, γ-L-Glutamyl-L-cysteinyl-glycine, GSH

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali

Scegli un formato

5 G
CHF 170.00
10 G
CHF 312.00
25 G
CHF 668.00
100 G
CHF 1’710.00

CHF 170.00

Spedizione prevista il15 maggio 2025

Richiedi un ordine bulk
Tutte le immagini(5)

Scegli un formato

Cambia visualizzazione
5 G
CHF 170.00
10 G
CHF 312.00
25 G
CHF 668.00
100 G
CHF 1’710.00

About This Item

Formula condensata:
H2NCH(CO2H)CH2CH2CONHCH(CH2SH)CONHCH2CO2H
Numero CAS:
70-18-8
Peso molecolare:
307.32
Beilstein:
1729812
Numero CE:
200-725-4
Numero MDL:
MFCD00065939
Codice UNSPSC:
12352209
ID PubChem:
24895241
NACRES:
NA.26

CHF 170.00

Spedizione prevista il15 maggio 2025

Richiedi un ordine bulk

Nome del prodotto

L-Glutathione reduced, suitable for cell culture, BioReagent, ≥98.0%, powder

Nome Commerciale

BioReagent

Livello qualitativo

300

Saggio

≥98.0%

Stato

powder

tecniche

cell culture | mammalian: suitable

Colore

white

Punto di fusione

192-195 °C (dec.) (lit.)

Solubilità

H2O: 50 mg/mL

Temperatura di conservazione

2-8°C

Stringa SMILE

N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O

InChI

1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
RWSXRVCMGQZWBV-WDSKDSINSA-N

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Categorie correlate

Amino Acid Sequence

γ-Glu-Cys-Gly

Applicazioni

May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

Azioni biochim/fisiol

Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
0000423930
0000423930
0000418642
0000418652
0000418653

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Lisong Ma et al.
The New phytologist, 208(2), 507-518 (2015-05-15)
Plant-invading microbes betray their presence to a plant by exposure of antigenic molecules such as small, secreted proteins called 'effectors'. In Fusarium oxysporum f. sp. lycopersici (Fol) we identified a pair of effector gene candidates, AVR2-SIX5, whose expression is controlled
Shinya Tsukiji et al.
Nature chemical biology, 5(5), 341-343 (2009-03-31)
Here we describe a method for the site-selective attachment of synthetic molecules into specific 'endogenous' proteins in vivo using ligand-directed tosyl (LDT) chemistry. This approach was applied not only for chemically labeling proteins in living cells, tissues and mice but
Jamuna Risal Paudel et al.
Molecular plant-microbe interactions : MPMI, 28(5), 569-579 (2015-01-22)
One or more effectors in the labial saliva (LS) of generalist Noctuid caterpillars activate plant signaling pathways to modulate jasmonate (JA)-dependent defense responses; however, the exact mechanisms involved have yet to be elucidated. A potential candidate in this phytohormone interplay
Hongwei Jiang et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(6), 2281-2291 (2015-02-15)
Osteoclast differentiation and function are highly dependent on the assembly and turnover of actin filaments, but little is known about the roles of actin binding proteins in these processes. Adseverin (Ads), a member of the gelsolin superfamily of actin capping
Mikito Owa et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(26), 9461-9466 (2014-07-01)
Outer arm dynein (OAD) in cilia and flagella is bound to the outer doublet microtubules every 24 nm. Periodic binding of OADs at specific sites is important for efficient cilia/flagella beating; however, the molecular mechanism that specifies OAD arrangement remains
Visualizza tutti i documenti correlati

Articoli

Glutathione in Cell Culture

Learn how glutathione and other components affect serum-free cell culture systems for protein biomanufacturing.

Amino Acid Codon Wheel

Amino Acid Codon Wheel for fast RNA translation. Find which amino acid is translated from your RNA sequence quickly and easily.

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Questions

1–6 of 6 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  4. What is the GSH level in plasma?

    1 answer

    1. It is in the micromolar range (approximately 4.5 mM). Chawla RK, Lewis FW, Kutner MH, et al. Plasma cysteine, cysteine, and glutathione in cirrhosis. Gastroenterology, 87, 770-776 (1984).

      Helpful?

  5. What are the GSH levels in human tissues?

    1 answer

    1. The GSH levels in human tissues normally range from 0.1 to 10 mM, most concentrated in the liver (up to 10 mM) and in the spleen, kidney, lens, erythrocytes, and leukocytes. Bremer HJ. Duran M, Kamerling JP, et al. Glutathione. In: Bremer HJ,DuranM, Kamerling JP, et al, eds. Distubance of Amino Acid Metabolism: Clinical Chemistry and Diagnosis. Baltimore-Munich: Urban and Schwarzenber; 1981:80-82.

      Helpful?

  6. How does the storage temperature relate to shipping conditions?

    1 answer

    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

      Helpful?

Reviews

No rating value

Active Filters

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.