Unfortunately, the solution stability of this product is not determined.
SML2156
Erlotinib hydrochloride
≥98% (HPLC)
Sinonimo/i:
774 hydrochloride, CP-358, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride, OSI-744 hydrochloride
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50 MG
CHF 75.70
100 MG
CHF 155.00
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Cambia visualizzazione
50 MG
CHF 75.70
100 MG
CHF 155.00
About This Item
Formula empirica (notazione di Hill):
C22H23N3O4 · HCl
Numero CAS:
Peso molecolare:
429.90
Numero MDL:
Codice UNSPSC:
12352200
NACRES:
NA.77
Prodotti consigliati
Saggio
≥98% (HPLC)
Stato
powder
Condizioni di stoccaggio
desiccated
Colore
white to beige
Solubilità
DMSO: 2 mg/mL, clear (warmed)
Temperatura di conservazione
−20°C
Stringa SMILE
Cl.N(c3cc(ccc3)C#C)c1ncnc2c1cc(c(c2)OCCOC)OCCOC
InChI
1S/C22H23N3O4.ClH/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22;/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25);1H
GTTBEUCJPZQMDZ-UHFFFAOYSA-N
Descrizione generale
Applicazioni
Erlotinib hydrochloride has been used to activate mitochondrial fragmentation in a human PANC-1 pancreatic cancer cell line.[2]
Azioni biochim/fisiol
EGFR kinase inhibitor; Antineoplastic
Erlotinib hydrochloride is an inhibitor of the receptor tyrosine kinase EGFR (epidermal growth factor receptor). It is used clinically for the treatment of non-small cell lung cancer (NSCLC) and in combination for metastatic pancreatic cancer.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Acute Tox. 4 Oral
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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How long is your erlotinib hydrochloride stable as aliquots dissolved in DMSO or water at -20 degrees? And how long is it stable when added to cell culture medium at 37 degrees at 5% CO2?
1 answer-
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