S0445

Anti-Serotonin 5-HT_2B Receptor antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Sinonimo/i: Anti-5-HT(2B), Anti-5-HT-2B, Anti-5-HT2B
• Numero MDL: MFCD01865274
• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 200
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• Reattività contro le specie: human
• Disponibilità: not available in Japan
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 4-6 μg/mL using human brain, neurons and glia
• N° accesso UniProt: P41595
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −70°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... HTR2B(3357) ; mouse ... Htr2b(15559) ; rat ... Htr2b(29581)

Descrizione

Descrizione generale

Multiplbe genes encode different subtypes of serotonin (5HT) receptor and are species specific. HTR2B is expressed in mammalian brain and is localized to GABA (γ-aminobutyric acid) producing neurons of dorsal hypothalamic nucleus. The HTR2B gene is mapped to human chromosome 2q37.1.

Immunogeno

synthetic peptide corresponding to the second extracellular loop of human serotonin 5-HT_2B receptor, conjugated KLH. The immunizing peptide has 80% homology with the rat gene and 93% homology with the mouse gene.

Azioni biochim/fisiol

The functions of serotonin (5HT) receptors are associated with sleep disorders, anxiety, depression and schizophrenia.

Descrizione del bersaglio

The Serotonin 5-HT_2B Receptor regulates cardiomyocyte development and growth. Activation of 5-HT_2B receptors may also contribute to initiation of sleep and to theta generation during W and PS under physiological conditions.

Stato fisico

solution in phosphate buffered saline containing ≤0.1% sodium azide

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): nwg
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable