L5668
Lipopolysaccharides from Escherichia coli O127:B8
Ready Made solution, 1 mg/mL
Sinonimo/i:
LPS
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2 ML
CHF 283.00
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Cambia visualizzazione
2 ML
CHF 283.00
About This Item
Prodotti consigliati
Origine biologica
Escherichia coli (O127:B8)
Livello qualitativo
Stato
buffered aqueous solution
Concentrazione
1 mg/mL
Colore
colorless to faint yellow
Solubilità
water: soluble
Condizioni di spedizione
wet ice
Temperatura di conservazione
2-8°C
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Descrizione generale
This product is a 0.2 um filtered aqueous solution containing 1 mg/mL of lipopolysaccharides (LPS) from E. coli serotype O127:B8. This LPS serotype has been used in studies of septic shock, to induce neutrophils, to induce NOS in rat brain and induce PAF synthesis in rat glomerular mesangial cells.
Applicazioni
Lipopolysaccharides (LPSs) are characteristic components of the cell wall of Gram-negative bacteria. LPS and its lipid A moiety stimulate cells of the innate immune system by the Toll-like receptor 4 (TLR4), a member of the Toll-like receptor protein family, which recognizes common pathogen-associated molecular-patterns (PAMPs).
Azioni biochim/fisiol
Lipopolysaccharides (LPS) are localized in the outer layer of the membrane and are, in noncapsulated strains, exposed on the cell surface. They contribute to the integrity of the outer membrane, and protect the cell against the action of bile salts and lipophilic antibiotics.
Nota sulla preparazione
The LPS used to prepare the solution have been phenol-extracted and chromatographically purified by gel filtration. Lipopolysaccharides prepared by phenol extraction contain up to 60% RNA and less than 1% protein. Subsequent purification by gel filtration chromatography removes much of protein present in the phenol-extracted LPS, but leaves a product that still contains 10-20% nucleic acids. Further purification using ion exchange chromatography yields an LPS product which contains <1% protein and <1% RNA.
Altre note
To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Prodotti correlati
N° Catalogo
Descrizione
Determinazione del prezzo
Codice della classe di stoccaggio
12 - Non Combustible Liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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Articoli
Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.
Contenuto correlato
Lipopolysaccharide (LPS) is a major component of Gram-negative bacteria, important for microbiological research.
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