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K1751

Sigma-Aldrich

Ketoprofen

Ketoprofen

≥98% (TLC), powder, non-steroidal anti-inflammatory compound

Sinonimo/i:

2-(3-Benzoylphenyl)propionic acid

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1 G
CHF 73.20
5 G
CHF 151.00
25 G
CHF 501.00
100 G
CHF 1’270.00

CHF 73.20


Spedizione prevista il16 marzo 2025


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Cambia visualizzazione
1 G
CHF 73.20
5 G
CHF 151.00
25 G
CHF 501.00
100 G
CHF 1’270.00

About This Item

Formula empirica (notazione di Hill):
C16H14O3
Numero CAS:
Peso molecolare:
254.28
Numero CE:
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.77

CHF 73.20


Spedizione prevista il16 marzo 2025


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product name

Ketoprofen, ≥98% (TLC)

Origine biologica

synthetic

Livello qualitativo

Saggio

≥98% (TLC)

Forma fisica

powder

Solubilità

ethanol: 50 mg/mL, clear, colorless to yellow

Ideatore

Bayer

Stringa SMILE

CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2

InChI

1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)
DKYWVDODHFEZIM-UHFFFAOYSA-N

Informazioni sul gene

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Descrizione generale

Ketoprofen belongs to the class of 2-arylpropionic acid.[1]

Applicazioni

Ketoprofen has been used:
  • as sample to analyse the effects of long storage period by chromatographic and microscopic techniques[2]
  • as a nonselective COX inhibitor to inject subcutaneously in rats to study its effect on stress/methamphetamine hydrochloride-induced changes in occludin, claudin-5 and COX-2 protein immunoreactivity, truncation of β-dystroglycan, brain water content and fluorescein isothiocyanate-dextran extravasation[3]
  • in phosphate buffer to study its ability to inhibit heat-induced denaturation of albumin[4]

Azioni biochim/fisiol

It serves as an efficient drug to treat ankylosing spondylitis, rheumatoid arthritis and osteoarthritis.[1] It also has antipyretic and analgesic effects. Ketoprofen prevents the action of prostaglandin synthetase.[5]
Non-steroidal anti-inflammatory compound that is selective for COX-1.

Caratteristiche e vantaggi

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pittogrammi

Skull and crossbonesEnvironment

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 3 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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In vitro chiral conversion, phase separation, and wave propagation in aged profen solutions
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Journal of Liquid Chromatography and Related Technologies, 32(9), 1359-1372 (2009)
Ekaterina Blinova et al.
International journal of molecular sciences, 22(18) (2021-09-29)
The possible involvement of p53 signaling, FGFR3 expression, and FGFR3 mutation rates in the prediction of the NMIBC anti-PD-L1 treatment response needs to be clarified. The main aim of our study was to explore predictive value of p53 expression, FGFR3
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The main goal of our study was to explore the wound-healing property of a novel cerium-containing N-acethyl-6-aminohexanoate acid compound and determine key molecular targets of the compound mode of action in diabetic animals. Cerium N-acetyl-6-aminohexanoate (laboratory name LHT-8-17) as a
Polyamidoamine dendrimers used as solubility enhancers of ketoprofen
Yiyun C, et al.
European Journal of Medicinal Chemistry, 40(12), 1390-1393 (2005)
Elisabeth Christiansen et al.
Journal of medicinal chemistry, 54(19), 6691-6703 (2011-08-23)
The free fatty acid receptor 1 (FFA1, also known as GPR40) enhances glucose-stimulated insulin secretion from pancreatic β-cells and is recognized as an interesting new target for treatment of type 2 diabetes. Several series of selective FFA1 agonists are already

Articoli

Human epithelial intestinal colonic organoids can be used as an alternative to Caco-2 drug permeability assays for drug screening and compound toxicity testing.

Discover Bioactive Small Molecules for Lipid Signaling Research

Chromatograms

application for HPLCapplication for HPLCapplication for HPLC

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