Product H7779, Retinoic acid p-hydroxyanilide, can be dissolved in DMSO (25 mg/ml) and ethanol (25 mg/ml).
H7779
Retinoic acid p-hydroxyanilide
≥95%
Sinonimo/i:
4-HPR, Fenretinide, N-(4-Hydroxyphenyl)retinamide
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Cambia visualizzazione
| Taglio della confezione | SKU | Disponibilità | Prezzo |
|---|---|---|---|
| 5 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 192.00 |
Informazioni su questo articolo
Formula empirica (notazione di Hill):
C26H33NO2
Numero CAS:
Peso molecolare:
391.55
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
Assay:
≥95%
Form:
powder
Servizio Tecnico
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Permettici di aiutartibiological source
synthetic (organic)
Quality Segment
assay
≥95%
form
powder
color
yellow to yellow-orange
storage temp.
−20°C
SMILES string
CC1=C(\C=C\C(C)=C\C=C\C(C)=C\C(=O)Nc2ccc(O)cc2)C(C)(C)CCC1
InChI
1S/C26H33NO2/c1-19(11-16-24-21(3)10-7-17-26(24,4)5)8-6-9-20(2)18-25(29)27-22-12-14-23(28)15-13-22/h6,8-9,11-16,18,28H,7,10,17H2,1-5H3,(H,27,29)/b9-6+,16-11+,19-8+,20-18+
InChI key
AKJHMTWEGVYYSE-FXILSDISSA-N
General description
Retinoic acid p-hydroxyanilide is a synthetic analog of retinoid.
Application
Biochem/physiol Actions
Retinoic acid p-hydroxyanilide, also called fenretinide, increases reactive oxygen species, activates caspases and induces apoptosis. It also inhibits dihydroceramide desaturase, leading to a decrease in ceramide biosynthesis.[1] Fenretinide may elicit anticancer activity in cultured human breast cancer cells.[1] It acts as an insulin antagonist and may be useful in treating insulin resistance.[1] Fenretinide or 4-HPR has chemotherapeutic potential and is cytotoxic to retinoic acid-resistant cancers.[2]
Vitamin A acid analogue with antiproliferative activity; induces apoptosis in malignant hemopoietic cell lines.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Classe di stoccaggio
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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Numero articolo commerciale globale
| SKU | GTIN |
|---|---|
| H7779-5MG | 04061833804735 |
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In what solvents can product H7779, Retinoic acid p-hydroxyanilide, be dissolved?
1 answer-
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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How can one store a solution of product H7779, Retinoic acid p-hydroxyanilide?
1 answer-
A solution of product H7779, Retinoic acid p-hydroxyanilide, can be aliquoted and stored at -20°C for up to 3 months. Solutions should be protect from light.
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