F5178

Flavin-Containing Monooxygenase-5, Microsomes human

recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)

• Sinonimo/i: FMO-5
• Classificazione EC (Enzyme Commission): 1.14.13.8 (BRENDA, IUBMB)
• Codice UNSPSC: 12352204
• NACRES: NA.54

Proprietà

• Ricombinante: expressed in baculovirus infected insect cells
• Livello qualitativo: 200
• Forma fisica: buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)
• Attività specifica: ≥700 units/mg protein
• PM: 55-60 kDa
• Confezionamento: vial of 2.5 mg
• N° accesso UniProt: P49326
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −70°C
• Informazioni sul gene: human ... FMO5(2330)

Descrizione

Applicazioni

FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

Azioni biochim/fisiol

FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

Definizione di unità

methyl p-tolyl sulfide oxidase activity: One unit will catalyze the production of 1.0 picomole of methyl p-tolyl sulfoxide.

Stato fisico

Solution in 100 mM potassium phosphate buffer, pH 7.4.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)