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Documenti fondamentali

C9426

Sigma-Aldrich

3-[(3-colamidopropil)dimetilammonio]-1-propansolfonato

BioReagent, suitable for electrophoresis, ≥98% (HPLC)

Sinonimo/i:

CHAPS

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1 G
CHF 178.00
5 G
CHF 623.00

CHF 178.00


Spedizione prevista il25 maggio 2025


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Cambia visualizzazione
1 G
CHF 178.00
5 G
CHF 623.00

About This Item

Formula empirica (notazione di Hill):
C32H58N2O7S · xH2O
Numero CAS:
Peso molecolare:
614.88 (anhydrous basis)
Numero MDL:
Codice UNSPSC:
12161902
ID PubChem:
NACRES:
NB.22

CHF 178.00


Spedizione prevista il25 maggio 2025


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Descrizione

zwitterionic

Nome Commerciale

BioReagent

Saggio

≥98% (HPLC)

Stato

powder

PM

614.88 g/mol (anhydrous basis)

tecniche

electrophoresis: suitable
protein quantification: suitable

Impurezze

<0.04% DMF

Punto di fusione

157 °C (dec.) (lit.)

Solubilità

water: 50 mg/mL, clear, colorless

Compatibilità

suitable for electrophoresis

Temperatura di conservazione

room temp

Stringa SMILE

O.C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C32H58N2O7S.H2O/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36;/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41);1H2/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-;/m1./s1
SJCUTFKCLFLIFE-JWTJKVBLSA-N

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Descrizione generale

CHAPS is a non-denaturing, zwitterionic sulfobetaine detergent. It is mild and solubilizes membrane proteins and receptors. It is useful for breaking protein-protein interactions. It is a derivative of the naturally occurring bile salts.[1] It has small micellar molecular weight (6,150) and high critical micellar concentration (6 - 10 mM) allowing it to be removed from samples by dialysis.

Applicazioni

CHAPS has been used:
  • For membrane permeabilization of cells[2]
  • As a component in lysis buffer for homogenization of liver tissues as well as adipose tissue[3][4]
  • As a component in denaturing buffer in enzyme characterization[5]
  • As a component of 2D- sample buffer in 2D electrophoresis[6]
  • For protein solubilization in isoelectric focusing[7]

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

Lot/Batch Number

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Questions

1–3 of 3 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. How do I store CHAPS, once it's dissolved in H2O?

    1 answer
    1. Solutions prepared at 100 mM in water are stable for at least 1 year when stored refrigerated. Note that a prepared solution is available. Please see the link below to review:
      https://www.sigmaaldrich.com/product/sigma/19899

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