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C5625

Sigma-Aldrich

Lithium carbamoylphosphate dibasic hydrate

≥85% (enzymatic)

Sinonimo/i:

CAP-Li2, Carbamoylphosphate dilithium salt, Carbamyl phosphate dilithium salt, Carbamyl phosphoric acid dilithium salt

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About This Item

Formula condensata:
NH2COOPO3Li2·xH2O
Numero CAS:
1866-68-8
Peso molecolare:
152.89 (anhydrous basis)
Beilstein:
6128395
Numero MDL:
MFCD00038144
Codice UNSPSC:
12161700
ID PubChem:
24892798
NACRES:
NA.25

product name

Lithium carbamoylphosphate dibasic hydrate,

Saggio

≥85% (enzymatic)

Forma fisica

powder

Qualità

may contain ~25% free acid (determined by PNMR)

Colore

white

Temperatura di conservazione

−20°C

Stringa SMILE

[Li+].[Li+].NC(=O)OP([O-])([O-])=O

InChI

1S/CH4NO5P.2Li/c2-1(3)7-8(4,5)6;;/h(H2,2,3)(H2,4,5,6);;/q;2*+1/p-2
TUHZSMCNIUXAIJ-UHFFFAOYSA-L

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Categorie correlate

Applicazioni

Carbamoylphosphate is used to study processes involving the mammalian urea cycle and nitrogen metabolism. Carbamoylphosphate is used as a substrate to identify and characterize ornithine transcarbamylase(s).

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302,H315,H319,H335

Classi di pericolo

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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Rita Kretz et al.
Molecular genetics and metabolism, 106(3), 375-378 (2012-05-12)
Carbamoylphosphate synthetase 1 (CPS1) is the first enzyme of the urea cycle. CPS1 deficiency is a rare autosomal-recessively inherited disorder that can lead to life-threatening hyperammonemia. Since there is no reliable biochemical marker for this disease, diagnosis relies on molecular
Mauricio Díaz-Muñoz et al.
Current medicinal chemistry, 17(21), 2253-2260 (2010-05-13)
Ornithine transcarbamylase (OTC; EC 2.1.3.3) is a one-carbon-unit transferring enzyme that synthesizes citrulline using ornithine and carbamoylphosphate as substrates. It is involved in the metabolic transformation of arginine and proline, and it participates in the urea cycle in vertebrates and
G Sainz et al.
European journal of biochemistry, 251(1-2), 528-533 (1998-03-10)
The pseudo-reverse reaction of Pseudomonas aeruginosa catabolic ornithine carbamoyltransferase in which arsenate is first coupled to citrulline followed by elimination of carbamylarsenate has been studied. Arsenate and citrulline saturation curves are sigmoidal. The different responsiveness of the transcarbamoylase to isosteric
Maria M Adeva et al.
Metabolism: clinical and experimental, 61(11), 1495-1511 (2012-08-28)
Free ammonium ions are produced and consumed during cell metabolism. Glutamine synthetase utilizes free ammonium ions to produce glutamine in the cytosol whereas glutaminase and glutamate dehydrogenase generate free ammonium ions in the mitochondria from glutamine and glutamate, respectively. Ammonia
Ruurdtje Hoekstra et al.
The international journal of biochemistry & cell biology, 43(10), 1483-1489 (2011-07-06)
For bioartificial liver application, cells should meet the following minimal requirements: ammonia elimination, drug metabolism and blood protein synthesis. Here we explore the suitability of HepaRG cells, a human cell line reported to differentiate into hepatocyte clusters and surrounding biliary

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