C4695

CHAPSO

BioXtra

• Sinonimo/i: 3-([3-Cholamidopropyl]dimethylammonio)-2-hydroxy-1-propanesulfonate
• Formula empirica (notazione di Hill): C₃₂H₅₈N₂O₈S
• Numero CAS: 82473-24-3
• Peso molecolare: 630.88
• Beilstein: 5842642
• Numero MDL: MFCD00081079
• Codice UNSPSC: 12161900
• ID PubChem: 24892713
• NACRES: NA.25

Proprietà

• Descrizione: zwitterionic
• Nome Commerciale: BioXtra
• Saggio: ≥98.0% (TLC)
• Stato: powder
• PM: micellar avg mol wt 7000
• Numero d'aggregazione: 11
• Impurezze: ≤0.0005% Phosphorus (P); ≤0.1% Insoluble matter (in Ethanol)
• Residuo alla calcinazione: ≤0.1%
• CMC: 8 mM (20-25°C); 8 mM (micellar weight =9960)
• Punto di fusione: 184-186 °C (lit.)
• Temp. transizione: cloud point 90 °C
• Solubilità: H₂O: 0.1 M at 20 °C, clear, colorless
• Anioni in tracce: chloride (Cl^-): ≤0.05%; sulfate (SO₄^2-): ≤0.05%
• Cationi in tracce: Al: ≤0.0005%; Ca: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Mg: ≤0.0005%; NH₄⁺: ≤0.05%; Na: ≤0.01%; Pb: ≤0.001%; Zn: ≤0.0005%
• Stringa SMILE: [H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]3([H])C[C@H](O)[C@]4(C)[C@]([H])(CC[C@@]4([H])[C@]3([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCC[N+](C)(C)CC(O)CS([O-])(=O)=O
• InChI: 1S/C32H58N2O8S/c1-20(7-10-29(39)33-13-6-14-34(4,5)18-23(36)19-43(40,41)42)24-8-9-25-30-26(17-28(38)32(24,25)3)31(2)12-11-22(35)15-21(31)16-27(30)37/h20-28,30,35-38H,6-19H2,1-5H3,(H-,33,39,40,41,42)/t20-,21+,22-,23?,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1; GUQQBLRVXOUDTN-XOHPMCGNSA-N

Descrizione

Descrizione generale

Chapso is a zwitterionic detergent derived from Chaps by the addition of a functional hydroxyl group. It is a nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group.

Applicazioni

A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.

Chapso has been used in a study to assess methods for high-throughput crystallization of membrane proteins. It has also been used in a study to investigate the effects of detergents on the structure of rhomboid proteases in a lipid environment.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves