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60178

Sigma-Aldrich

Potassium cyanide

BioUltra, ≥98.0% (AT)

Sinonimo/i:

KCN, Potassium salt of hydrocyanic acid

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25 G
CHF 34.20
100 G
CHF 104.00

CHF 34.20

Disponibile per la spedizione il31 marzo 2025Dettagli

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Cambia visualizzazione
25 G
CHF 34.20
100 G
CHF 104.00

About This Item

Formula condensata:
KCN
Numero CAS:
151-50-8
Peso molecolare:
65.12
Beilstein:
3593645
Numero CE:
205-792-3
Numero MDL:
MFCD00011397
Codice UNSPSC:
12352302
ID PubChem:
57651730
NACRES:
NA.25

CHF 34.20

Disponibile per la spedizione il31 marzo 2025Dettagli

Richiedi un ordine bulk

Origine biologica

synthetic

Livello qualitativo

200

Nome Commerciale

BioUltra

Saggio

≥98.0% (AT)

Stato

crystalline

Impurezze

insoluble matter, passes filter test

pH

11.0-13.0 (25 °C, 1 M in H2O)

Punto di fusione

634 °C (lit.)

Solubilità

H2O: 1 M at 20 °C, clear, colorless

Anioni in tracce

chloride (Cl-): ≤200 mg/kg
sulfate (SO42-): ≤400 mg/kg
sulfide (S2-): ≤5 mg/kg
thiocyanate (SCN-): ≤100 mg/kg

Cationi in tracce

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤100 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤5000 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

1 M in H2O

Assorbanza UV

λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03

Stringa SMILE

[K]C#N

InChI

1S/CN.K/c1-2;
YUZRZFQHUCKACF-UHFFFAOYSA-N

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Applicazioni

Potassium cyanide is use to inhibit oxidative phosphorylation reactions in a wide variety of biological systems and applications.

Altre note

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
Blocks electron transport to oxygen via cytochrome oxidase, hence employed in the determination of succinate dehydrogenase in submitochondrial particles by preventing substantial loss of succinate by electron flux to O2[1][2]

Avvertenze

Danger

Indicazioni di pericolo

H290,H300 + H310 + H330,H372,H410

Classi di pericolo

Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Met. Corr. 1 - STOT RE 1

Organi bersaglio

Thyroid

Rischi supp

EUH032

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
BCCL8700
BCCH3565
BCCC6860
BCCC5573
BCBT2916

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Mammalian succinate dehydrogenase.
B A Ackrell et al.
Methods in enzymology, 53, 466-483 (1978-01-01)
Pascaline Clerc et al.
Journal of bioenergetics and biomembranes, 39(2), 158-166 (2007-04-21)
We have studied the effect of nitric oxide (NO) and potassium cyanide (KCN) on oxidative phosphorylation efficiency. Concentrations of NO or KCN that decrease resting oxygen consumption by 10-20% increased oxidative phosphorylation efficiency in mitochondria oxidizing succinate or palmitoyl-L-carnitine, but
EPR and other properties of succinate dehydrogenase.
T Ohnishi et al.
Methods in enzymology, 53, 483-495 (1978-01-01)
Yudong Wang et al.
The Journal of biological chemistry, 285(39), 29834-29841 (2010-07-29)
Fatty acid β-oxidation (FAO) and oxidative phosphorylation (OXPHOS) are key pathways involved in cellular energetics. Reducing equivalents from FAO enter OXPHOS at the level of complexes I and III. Genetic disorders of FAO and OXPHOS are among the most frequent
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Frontiers in cell and developmental biology, 8, 603688-603688 (2021-01-08)
Arginyltransferase 1 (ATE1) is an evolutionary-conserved eukaryotic protein that localizes to the cytosol and nucleus. It is the only known enzyme in metazoans and fungi that catalyzes posttranslational arginylation. Lack of arginylation has been linked to an array of human
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Questions

1–3 of 3 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Hello, please can this type be used for laboratory experiments on experimental rodents 

    1 answer

    1. Product No. 60178 is not intended for live animal testing.

      Helpful?

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