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46943

Sigma-Aldrich

Fluorescein dilaurate

suitable for fluorescence, ≥97.0% (HPCE)

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About This Item

Formula empirica (notazione di Hill):
C44H56O7
Numero CAS:
7308-90-9
Peso molecolare:
696.91
Beilstein:
6034843
Numero CE:
230-764-2
Numero MDL:
MFCD00038409
Codice UNSPSC:
12352106
ID PubChem:
57650888
NACRES:
NA.32

Saggio

≥97.0% (HPCE)

Forma fisica

powder

Solubilità

ethanol: soluble

Fluorescenza

λex 490 nm; λem 514 nm in 0.1 M Tris pH 8.0 (esterase)

Compatibilità

suitable for fluorescence

Stringa SMILE

CCCCCCCCCCCC(=O)Oc1ccc2c(Oc3cc(OC(=O)CCCCCCCCCCC)ccc3C24OC(=O)c5ccccc45)c1

InChI

1S/C44H56O7/c1-3-5-7-9-11-13-15-17-19-25-41(45)48-33-27-29-37-39(31-33)50-40-32-34(49-42(46)26-20-18-16-14-12-10-8-6-4-2)28-30-38(40)44(37)36-24-22-21-23-35(36)43(47)51-44/h21-24,27-32H,3-20,25-26H2,1-2H3
MYTRGBGGRICZGN-UHFFFAOYSA-N

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Applicazioni

Fluorescein dilaurate is suitable as fluorogenic substrate for esterases/lipases and used in the pancreolauryl test for chronic pancreatitis.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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F Seibold et al.
Journal of clinical gastroenterology, 22(3), 202-206 (1996-04-01)
Pancreatic autoantibodies (PABs) are found in 31% of patients with Crohn's disease (CD), but they do not correlate with the activity of intestinal disease or the incidence of acute pancreatitis. Exocrine pancreatic insufficiency has been observed in patients with CD.
M Fuchs et al.
Zentralblatt fur Chirurgie, 120(6), 472-477 (1995-01-01)
In a follow up study 19 patients after Billroth-I, 22 patients after Billroth-II-resection and 38 patients after total gastrectomy (23 with Roux-Y-reconstruction and 15 with Longmire-Gütgemann) underwent a stool fat determination and an indirect pancreatic function test with fluorescein dilaurate
R S Chowdhury et al.
Alimentary pharmacology & therapeutics, 17(6), 733-750 (2003-03-19)
Pancreatic function tests are most commonly used to diagnose chronic pancreatitis. These tests include tests which document exocrine or endocrine gland insufficiency and tests which instead measure gradations of decreased secretory capacity. The tests in the former category generally become
L M Burrell et al.
Scandinavian journal of clinical and laboratory investigation, 51(8), 675-680 (1991-12-01)
We have employed an oral test of pancreatic digestive function using fluorescein dilaurate (a substrate for pancreatic cholesterol ester hydrolase), administered together with pancreatic enzyme supplements, in order to test the hypothesis that urinary excretion of fluorescein provides a simple
I A Murray et al.
Postgraduate medical journal, 79(934), 471-473 (2003-09-05)
To audit the specificity and value of the pancreolauryl test (PLT) for the diagnosis of pancreatic insufficiency. A retrospective case note review of 47 patients who had a PLT during three consecutive years. A 650 bedded district general hospital. Patient
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