PHR1909

Atenolol

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinonimo/i: Atenolol, (±)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide, 4-[2′-Hydroxy-3′-(isopropylamino)propoxy]phenylacetamide
• Formula empirica (notazione di Hill): C₁₄H₂₂N₂O₃
• Numero CAS: 29122-68-7
• Peso molecolare: 266.34
• Numero CE: 249-451-7
• Numero MDL: MFCD00057645
• Codice UNSPSC: 41116107
• NACRES: NA.24

Proprietà

• Grado: certified reference material; pharmaceutical secondary standard
• Livello qualitativo: 300
• agenzia: traceable to BP 492; traceable to Ph. Eur. A1340000; traceable to USP 1044403
• Famiglia di API: atenolol
• Forma fisica: powder
• CdA: current certificate can be downloaded
• Confezionamento: pkg of 500 mg
• applicazioni: pharmaceutical
• Temperatura di conservazione: 2-30°C
• Stringa SMILE: CC(C)NCC(O)COc1ccc(CC(N)=O)cc1
• InChI: 1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18); METKIMKYRPQLGS-UHFFFAOYSA-N
• Informazioni sul gene: human ... ADRB1(153)

Descrizione

Descrizione generale

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Atenolol is a beta-1 blocker used in the treatment of various cardiovascular diseases.

Applicazioni

This pharmaceutical secondary standard can also be used as follows:

• Simultaneous analysis of atenolol and nifedipine using magnesium oxide-nanoplatelets (MgO-NPLs) modified screen-printed electrodes (SPEs) by differential pulse voltammetry (DPV) from pharmaceutical dosage forms and urine samples
• Voltammetric determination of amlodipine besylate and atenolol in their combined pharmaceutical formulations using a cathodically pretreated-boron doped diamond electrode (CP-BDDE)
• Spectrofluorimetric determination of atenolol using gold nanoparticles (AuNPs) based photo probes in commercial tablets
• Amperometric estimation of atenolol using bismuth vanadate-bismuth(III) oxide (BiVO₄–Bi₂O) composite electrode in pharmaceutical formulations and human urine samples
• Development of a reversed phase-high performance liquid chromatography (RP-HPLC) method coupled to a photodiode array detector (PDA) for the quantitative analysis of atenolol and trimetazidine in human urine and pharmaceutical tablets

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAC0712 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable