A7655

Atenolol

≥98% (TLC), powder, β₁-adrenoceptor antagonist

• Sinonimo/i: (±)-4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide, 4-[2′-Hydroxy-3′-(isopropylamino)propoxy]phenylacetamide
• Formula empirica (notazione di Hill): C₁₄H₂₂N₂O₃
• Numero CAS: 29122-68-7
• Peso molecolare: 266.34
• NACRES: NA.77
• PubChem Substance ID: 24277748
• UNSPSC Code: 12352200
• EC Number: 249-451-7
• MDL number: MFCD00057645
• Assay: ≥98% (TLC)
• Form: powder

Proprietà

• Nome del prodotto: Atenolol, ≥98% (TLC), powder
• Quality Segment: 200
• assay: ≥98% (TLC)
• form: powder
• color: white to off-white
• solubility: H₂O: 0.3 mg/mL, DMSO: 18 mg/mL, ethanol: 3.4 mg/mL
• originator: AstraZeneca
• SMILES string: CC(C)NCC(O)COc1ccc(CC(N)=O)cc1
• InChI: 1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)
• InChI key: METKIMKYRPQLGS-UHFFFAOYSA-N
• Gene Information: human ... ADRB1(153) ; rat ... Adrb1(24925)

Descrizione

Application

Atenolol is a β-adrenergic blocker and used in the management of hypertension. Atenolol has antianginal and antiarrhythmic properties.

Biochem/physiol Actions

Selective β₁-adrenoceptor antagonist; antihypertensive; antianginal; antiarrhythmic.

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Other Notes

Shelf-life of the solid is at least three years.

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• Che succede?: WGK 2
• Punto di infiammabilità (°F): Not applicable
• Punto di infiammabilità (°C): Not applicable
• DPI (dispositivi di protezione individuale): Eyeshields, Gloves, type N95 (US)