N0600000

Nicotinamide

European Pharmacopoeia (EP) Reference Standard

• Sinonimo/i: Niacinamide, Nicotinic acid amide, Pyridine-3-carboxylic acid amide, Vitamin B₃, Vitamin PP
• Formula empirica (notazione di Hill): C₆H₆N₂O
• Numero CAS: 98-92-0
• Peso molecolare: 122.12
• Beilstein: 383619
• Numero MDL: MFCD00006395
• Codice UNSPSC: 41116107
• ID PubChem: 329818447
• NACRES: NA.24

Proprietà

• Origine biologica: synthetic
• Grado: pharmaceutical primary standard
• Famiglia di API: nicotinamide
• Stato: solid
• Produttore/marchio commerciale: EDQM
• tecniche: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Punto di fusione: 128-131 °C (lit.)
• applicazioni: pharmaceutical (small molecule)
• Formato: neat
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: NC(=O)c1cccnc1
• InChI: 1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9); DFPAKSUCGFBDDF-UHFFFAOYSA-N

Descrizione

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Nicotinamide belongs to the group of water-soluble B vitamins. It is generally formed from nicotinic acid (vitamin B₃). It is available in food products and is utilized for the treatment of pellagra, psoriasis, schizophrenia, and type I diabetes. It is also known for its anti-inflammatory activity.[1][2]

Applicazioni

Nicotinamide can be used as an EP reference standard for the quantification of the analyte in pharmaceutical formulations and biological fluids by chromatography, UV-visible spectrophotometry and multivariate analysis.[1][3][4][5]

Azioni biochim/fisiol

Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H319
• Consigli di prudenza: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Classi di pericolo: Eye Irrit. 2
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): 302.0 °F - closed cup
• Punto d’infiammabilità (°C): 150 °C - closed cup