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Supelco

5-Hydroxydiclofenac

analytical standard

Sinonimo/i:

5-OH-DCF, 2-[(2,6-Dichlorophenyl)amino]-5-hydroxybenzeneacetic acid

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About This Item

Formula empirica (notazione di Hill):
C14H11Cl2NO3
Numero CAS:
Peso molecolare:
312.15
Beilstein:
4199419
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Saggio

≥97.0% (HPLC)

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

pharmaceutical

Formato

neat

Temperatura di conservazione

−20°C

Stringa SMILE

OC(CC1=CC(O)=CC=C1NC2=C(Cl)C=CC=C2Cl)=O

InChI

1S/C14H11Cl2NO3/c15-10-2-1-3-11(16)14(10)17-12-5-4-9(18)6-8(12)7-13(19)20/h1-6,17-18H,7H2,(H,19,20)
VNQURRWYKFZKJZ-UHFFFAOYSA-N

Categorie correlate

Descrizione generale

5-Hydroxydiclofenac, a monohydroxylated metabolite of diclofenac, belongs to the class of non-steroidal anti-inflammatory compounds.29}

Applicazioni

5-Hydroxydiclofenac may be used as an analytical standard for the determination of the analyte in biological samples and wastewater by liquid chromatography (LC) based techniques.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pittogrammi

Exclamation markEnvironment

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Simultaneous determination of diclofenac, its human metabolites and microbial nitration/nitrosation transformation products in wastewaters by liquid chromatography/quadrupole-linear ion trap mass spectrometry
Osorio V, et al.
Journal of Chromatography A, 1347(1), 63-71 (2014)
High-performance liquid chromatographic method for the routine determination of diclofenac and its hydroxy and methoxy metabolites from in vitro systems
Schmitz G, et al.
Journal of Chromatography. B, Biomedical Applications, 620(1), 158-163 (1993)
Klaudia Świacka et al.
Marine pollution bulletin, 141, 249-255 (2019-04-09)
Interest in the presence of pharmaceutically active compounds in the aquatic environment has been growing for over 20 years, yet very few studies deal with the metabolism of pharmaceuticals in marine organisms. In this study, the bioaccumulation under short-term conditions and
Jing Shi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 191, 1-7 (2017-10-02)
A novel flow injection chemiluminescence immunoassay for simple, sensitive and low-cost detection of diclofenac was established based on specific binding of antigen and antibody. Carboxylic resin beads used as solid phase carrier materials provided good biocompatibility and large surface-to-volume ratio
High-performance liquid chromatographic determination of diclofenac and its monohydroxylated metabolites in biological fluids
Godbillon J, et al.
Journal of Chromatography. B, Biomedical Applications, 338(1), 151-159 (1985)

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