1.00164

Acido borico

cryst., EMPROVE^® API, Ph. Eur., BP, NF

• Sinonimo/i: Orthoboric acid, Trihydroxidoboron
• Formula condensata: H₃BO₃
• Numero CAS: 10043-35-3
• Peso molecolare: 61.83
• Numero MDL: MFCD00011337
• Codice UNSPSC: 12352106
• Numero indice EU: 233-139-2

Proprietà

• agenzia: BP; NF; Ph. Eur.
• Livello qualitativo: 600
• Tensione di vapore: 2.6 mmHg ( 20 °C)
• Nome Commerciale: EMPROVE^® API
• Saggio: 99.5-100.5% (alkalimetric)
• Stato: solid
• Potenza: 2660 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• pH: 3.8-4.8 (20 °C, 33 g/L in H₂O)
• Punto di fusione: 160 °C (dec.) (lit.)
• Solubilità: 49.2 g/L
• Densità: 1.489 g/cm³ at 23 °C
• Densità bulk: 400‑600 kg/m³
• Anioni in tracce: sulfate (SO₄^2-): ≤0.04%
• Cationi in tracce: As: ≤0.0001%; heavy metals (as Pb): ≤0.0015%
• applicazioni: liquid formulation; ophthalmics; parenterals; pharmaceutical; semi-solid formulation
• Temperatura di conservazione: 2-25°C
• Stringa SMILE: OB(O)O
• InChI: 1S/BH3O3/c2-1(3)4/h2-4H; KGBXLFKZBHKPEV-UHFFFAOYSA-N

Descrizione

Descrizione generale

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Applicazioni

Boric acid as an active ingredient is used in ophthalmic drugs, as antiseptic for cuts and burns, as well as antibacterial for dermatological treatments such as acne and athlete foot. Boric acid Emprove^® API is manufactured according to ICH Q7 guidelines. A CEP and an US-DMF are available.

Note legali

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H360FD
• Consigli di prudenza: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classi di pericolo: Repr. 1B
• Codice della classe di stoccaggio: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable