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D-067

Supelco

Digitoxin solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formula empirica (notazione di Hill):
C41H64O13
Numero CAS:
71-63-6
Peso molecolare:
764.94
Codice UNSPSC:
41116107
NACRES:
NA.24

Grado

certified reference material

Livello qualitativo

300

Stato

liquid

Caratteristiche

Snap-N-Spike®/Snap-N-Shoot®

Confezionamento

ampule of 1 mL

Produttore/marchio commerciale

Cerilliant®

Concentrazione

1.0 mg/mL in methanol

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

applicazioni

pharmaceutical (small molecule)

Formato

single component solution

Temperatura di conservazione

−20°C

Stringa SMILE

CC1OC(CC(O)C1O)OC2C(O)CC(OC2C)OC3C(O)CC(OC3C)OC4CCC5(C)C(CCC6C5CCC7(C)C(CCC67O)C8=CC(=O)OC8)C4

InChI

1S/C41H64O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37)43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,20-22,24-31,33-38,42-44,46-47H,6-13,15-19H2,1-5H3
WDJUZGPOPHTGOT-UHFFFAOYSA-N

Descrizione generale

A cardiac glycoside and antiarrhythmic drug similar in structure and effect to digoxin. Digitoxin is monitored by clinical labs to ensure patients remain within the drug′s therapeutic range.

Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Avvertenze

Danger

Indicazioni di pericolo

H225,H301 + H311 + H331,H370

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organi bersaglio

Eyes,Central nervous system

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

49.5 °F - closed cup

Punto d’infiammabilità (°C)

9.7 °C - closed cup

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Certificati d'analisi (COA)

Lot/Batch Number

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Digoxin analytical standard

Supelco

D6003

Digoxin

Digitonin, High Purity CAS 11024-24-1 is a non-ionic detergent commonly used to solubilize membrane-bound proteins.

Millipore

300410

Digitonin, High Purity

Digitonina ~50% (TLC)

Sigma-Aldrich

D5628

Digitonina

Digitonina Used as non-ionic detergent

Sigma-Aldrich

D141

Digitonina

Termination of refractory focal status epilepticus by the P-glycoprotein inhibitor verapamil.
S Pirker et al.
European journal of neurology, 18(12), e151-e151 (2011-11-22)
Ryan Matsuda et al.
Journal of chromatography. A, 1265, 114-122 (2012-10-25)
High-performance affinity chromatography (HPAC) was used to examine the changes in binding that occur for the sulfonylurea drug glibenclamide with human serum albumin (HSA) at various stages of glycation for HSA. Frontal analysis on columns containing normal HSA or glycated
An elderly man with atrial fibrillation and exacerbated diabetes.
Ketil Arne Espnes et al.
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 132(9), 1103-1105 (2012-05-23)
Hosam A Elbaz et al.
Toxicology and applied pharmacology, 258(1), 51-60 (2011-11-01)
Mechanisms of digitoxin-inhibited cell growth and induced apoptosis in human non-small cell lung cancer (NCI-H460) cells remain unclear. Understanding how digitoxin or derivate analogs induce their cytotoxic effect below therapeutically relevant concentrations will help in designing and developing novel, safer
Arne Hønnås et al.
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 130(13), 1334-1336 (2010-07-03)
In 2007, new Norwegian guidelines suggested that serum concentrations of digitoxin should be in the interval 8 - 15 nmol/l, which is about 50 % lower than previous recommendations. We studied trends in dosing and serum concentrations of digitoxin in
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