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850336P

Avanti

MAPCHO-12

Avanti Research - A Croda Brand

Sinonimo/i:

DPC; Fos-Choline-12; FOS12; FC-12

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About This Item

Formula empirica (notazione di Hill):
C17H38NO4P
Numero CAS:
Peso molecolare:
351.46
Codice UNSPSC:
12352211
NACRES:
NA.25

Descrizione

n-dodecylphosphocholine

Saggio

>99% (TLC)

Forma fisica

powder

Confezionamento

pkg of 1 × 1 g (850336P-1g)
pkg of 1 × 25 g (850336P-25g)
pkg of 1 × 5 g (850336P-5g)

Produttore/marchio commerciale

Avanti Research - A Croda Brand

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

InChI

1S/C17H38NO4P/c1-5-6-7-8-9-10-11-12-13-14-16-21-23(19,20)22-17-15-18(2,3)4/h5-17H2,1-4H3
QBHFVMDLPTZDOI-UHFFFAOYSA-N

Descrizione generale

Dodecylphosphocholine is a structural analog of lauroyl lysophosphatidylcholine that is more stable to hydrolytic degradation. The lipid is often used as a detergent for membrane protein solubilization and purification.Dodecylphosphocholine has been shown to improve paracellular permeability of hydrophilic compounds by modulating the tight junctions. This may have implications on its use for oral or nasal drug delivery.
MAPCHO-12 or n-dodecylphosphocholine is a detergent with short chain.

Applicazioni

MAPCHO-12 is suitable for use as detergent for B. subtilis cytochrome b558 protein for nuclear magnetic resonance experiments. It is also suitable for use in the purification of cytoplasmic tail of gp41 (gp41CT) protein and micelle preparation.

Azioni biochim/fisiol

MAPCHO-12 or n-dodecylphosphocholine in combination with 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is used for membrane-mimetic bicelle system for orientation based studies in membrane proteins. It provides a zwitterionic surface in the membrane micelle structure.

Confezionamento

125 mL Amber Wide Mouth Glass Bottle with Screw Cap (850336P-5g)
20 mL Clear Glass Screw Cap Vial (850336P-1g)
250 mL Amber Wide Mouth Glass Bottle with Screw Cap (850336P-25g)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC
MAPCHO is a trademark of Avanti Polar Lipids, LLC

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Fusion of host and viral membranes is a crucial step during infection by enveloped viruses. In the structurally-defined "class I″ viral glycoproteins, the formation of a highly stable α-helical bundle by the ectodomain of the fusion subunit (e.g., GP2 for
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Sikorska E, et al.
Journal of Thermal Analysis and Calorimetry, 123(1), 511-523 (2016)

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