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W422312

Sigma-Aldrich

Betaine

≥98%

Sinonimo/i:

(Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine

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W422312-SAMPLE-K
CHF 152.00
1 KG
CHF 266.00
5 KG
CHF 588.00

CHF 152.00


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Cambia visualizzazione
W422312-SAMPLE-K
CHF 152.00
1 KG
CHF 266.00
5 KG
CHF 588.00

About This Item

Formula condensata:
(CH3)3N+CH2COO-
Numero CAS:
Peso molecolare:
117.15
Numero FEMA:
4223
Beilstein:
3537113
Numero MDL:
Codice UNSPSC:
12164502
NACRES:
NA.21

CHF 152.00


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Grado

Halal
Kosher

Conformità normativa

FDA 21 CFR 117

Saggio

≥98%

applicazioni

flavors and fragrances

Documentazione

see Safety & Documentation for available documents

Allergene alimentare

no known allergens

Organolettico

odorless

Stringa SMILE

C[N+](C)(C)CC([O-])=O

InChI

1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
KWIUHFFTVRNATP-UHFFFAOYSA-N

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Applicazioni


  • Assessment between antiseptic and normal saline for negative pressure wound therapy with instillation and dwell time in diabetic foot infections.: Betaine is evaluated for its antimicrobial properties in a clinical setting, comparing its effectiveness with standard treatments for enhancing wound healing and preventing infection in diabetic foot ulcers. This study contributes to the optimization of therapeutic strategies for chronic wounds (Zhao J et al., 2024).

  • [Clinical features and follow-up study on 55 patients with adolescence-onset methylmalonic acidemia].: This research includes betaine in the treatment protocols for patients with methylmalonic acidemia, analyzing its effectiveness in reducing symptoms and improving metabolic profiles. The study provides valuable insights into the management of this rare metabolic disorder (Ma X et al., 2024).

Azioni biochim/fisiol

End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.[1]

Esclusione di responsabilità

For R&D or non-EU Food use. Not for retail sale.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

Lot/Batch Number

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1 of 4

Shu Yang et al.
Journal of the science of food and agriculture, 100(4), 1486-1494 (2019-11-23)
We reported previously that maternal betaine promotes hepatic insulin-like growth factor (IGF2) expression in F1 offspring rats through hypermethylation of the IGF2/H19 imprinting control region (ICR). It remains unknown whether this acquired trait can be transmitted to the F2 generation.
Nannan Zhao et al.
European journal of nutrition, 59(4), 1707-1716 (2019-06-16)
Excessive exposure of glucocorticoids activates adipose lipolysis, increases circulating free fatty acids, and contributes to ectopic lipid deposition in liver and skeletal muscle. Our previous study demonstrated that maternal betaine supplementation attenuates glucocorticoid-induced hepatic lipid accumulation in rat offspring. However
Yang Yang et al.
Molecular nutrition & food research, 64(8), e1900823-e1900823 (2020-02-06)
Betaine serves as a methyl donor for DNA methylation. Here, the effects of betaine on hippocampal expression of neurogenesis genes and their DNA methylation status across three generations are investigated. Pregnant rats (F0) are fed control and betaine-supplemented diets throughout

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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