T85308
Tris(2-chloroethyl)amine hydrochloride
98%
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About This Item
Formula condensata:
(ClCH2CH2)3N·HCl
Numero CAS:
Peso molecolare:
240.99
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
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Livello qualitativo
Saggio
98%
Punto di fusione
127-130 °C (lit.)
Stringa SMILE
Cl.ClCCN(CCCl)CCCl
InChI
1S/C6H12Cl3N.ClH/c7-1-4-10(5-2-8)6-3-9;/h1-6H2;1H
VEAUDLLZYJVHRI-UHFFFAOYSA-N
Categorie correlate
Avvertenze
Danger
Indicazioni di pericolo
Classi di pericolo
Acute Tox. 2 Oral - Carc. 2 - Skin Corr. 1B
Codice della classe di stoccaggio
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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Landmark article Sept. 21, 1946: Nitrogen mustard therapy. Use of methyl-bis(beta-chloroethyl)amine hydrochloride and tris(beta-chloroethyl)amine hydrochloride for Hodgkin's disease, lymphosarcoma, leukemia and certain allied and miscellaneous disorders. By Louis S. Goodman, Maxwell M. Wintrobe, William Dameshek, Morton J. Goodman, Alfred Gilman and Margaret T. McLennan.
L S Goodman et al.
JAMA, 251(17), 2255-2261 (1984-05-04)
Qing Liu et al.
Wei sheng yan jiu = Journal of hygiene research, 38(5), 528-530 (2009-11-03)
To investigate the influence factors of human peripheral blood B lymphocyte transformation by epstein-barr virus (EBV). EB virus was obtained from B95-8 supernatant and quantitated by quantitative PCR amplification. The concentration of cyclosporine A (CSA) concentration of lymphocytes and different
I Sýkora et al.
Mutation research, 266(2), 291-297 (1992-04-01)
The genetic effect of the cytostatic trichlormethine hydrochloride (TS-160 Spofa) was assessed after a 1-week administration using the dominant lethal mutation test (DLM) and the sperm abnormality test. The dosage was 0.5 mg/kg for 7 consecutive days, an equivalent of
I Sýkora et al.
Neoplasma, 28(5), 565-574 (1981-01-01)
The cytostatic TS-160 (trichloromethine hydrochloride, tris-/2-chloroethyl/amine hydrochloride) was injected subcutaneously into SPF Wistar rats of both sexes. After all doses used, spindle-cell or even polymorphocellular sarcomas developes at the injection sites in both sexes: after the dose of 0.1 mg/kg
N I Ryabchenko et al.
General physiology and biophysics, 10(1), 41-48 (1991-02-01)
The dynamic of chromatin degradation was studied in thymocytes and LS/BL tumour cells. In permeabilised LS/BL cells, the rate of DNA degradation induced by endogenous calcium and magnesium-dependent endonuclease was approx. 25 times slower than in thymocytes. In LS/BL cells
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