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G6600

Sigma-Aldrich

Glycine methyl ester hydrochloride

99%, for peptide synthesis

Sinonimo/i:

Glycine methyl ester·HCl, Methyl glycinate hydrochloride

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About This Item

Formula condensata:
NH2CH2COOCH3 · HCl
Numero CAS:
Peso molecolare:
125.55
Beilstein:
3593644
Numero CE:
Numero MDL:
Codice UNSPSC:
12352209
eCl@ss:
32160406
ID PubChem:
NACRES:
NA.22

product name

Glycine methyl ester hydrochloride, 99%

Saggio

99%

Forma fisica

powder, crystals or chunks

Impiego in reazioni chimiche

reaction type: solution phase peptide synthesis

Colore

white

Punto di fusione

175 °C (dec.) (lit.)

applicazioni

peptide synthesis

Stringa SMILE

Cl.COC(=O)CN

InChI

1S/C3H7NO2.ClH/c1-6-3(5)2-4;/h2,4H2,1H3;1H
COQRGFWWJBEXRC-UHFFFAOYSA-N

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Descrizione generale

Glycine methyl ester hydrochloride, also known as methyl glycinate hydrochloride, is a derivative of glycine, used in the preparation of amino acids and organic compounds.

Applicazioni

Glycine methyl ester hydrochloride is used to synthesize cyclophosphazene compounds with amino acid esters as side groups. Additionally, it can be utilized to synthesize peptides in aqueous medium, which makes it a green method for peptide formation.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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International journal of peptide and protein research, 21(4), 440-450 (1983-04-01)
The reactivity of the carboxyl groups in bovine growth hormone was studied by reaction with 1-ethyl-3(3-dimethylaminopropyl) carbodiimide in the presence of an excess of glycinemethylester. Localization in the molecule of the various kinetically distinguishable carboxyl groups was achieved. Highest reactivity
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Journal of combinatorial chemistry, 7(4), 618-621 (2005-07-12)
An easy and convenient microwave-assisted synthesis of N-alkylated glycine methyl esters is described. Parallel and nonparallel combinatorial methods are described and compared. The described reactions are reductive alkylations of several aldehydes and glycine methyl ester in the presence of NaBH3CN.
C Alarcon et al.
Bioscience reports, 5(7), 581-587 (1985-07-01)
Glycine methyl ester, an inhibitor of transglutaminase, decreased glucose-stimulated insulin release and delayed proinsulin conversion in rat pancreatic islets pulse-labelled with L-[4-3H]phenylalanine. Sarcosine methyl ester, which does not inhibit transglutaminase activity, failed to affect insulin release and proinsulin conversion. The

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