852279
2′-Deoxyinosine
99%
Sinonimo/i:
9-(2-Deoxy-β-D-ribofuranosyl)hypoxanthine
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About This Item
Formula empirica (notazione di Hill):
C10H12N4O4
Numero CAS:
Peso molecolare:
252.23
Beilstein:
33517
Numero CE:
Numero MDL:
Codice UNSPSC:
12352103
ID PubChem:
Prezzi e disponibilità al momento non sono disponibili
Prodotti consigliati
Livello qualitativo
Saggio
99%
Stato
powder
Gruppo funzionale
ether
hydroxyl
Stringa SMILE
OC[C@H]1O[C@H](C[C@@H]1O)n2cnc3C(=O)NC=Nc23
InChI
1S/C10H12N4O4/c15-2-6-5(16)1-7(18-6)14-4-13-8-9(14)11-3-12-10(8)17/h3-7,15-16H,1-2H2,(H,11,12,17)/t5-,6+,7+/m0/s1
VGONTNSXDCQUGY-RRKCRQDMSA-N
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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Raphaelle Fanciullino et al.
Pharmaceutical research, 22(12), 2051-2057 (2005-10-14)
The aims of this study were to develop a stealth, pegylated liposomal formulation of 2'-deoxyinosine (d-Ino), a 5-fluorouracil (5-FU) modulator, to evaluate its efficacy in vitro and in tumor-bearing mice, and to study its pharmacokinetics in rats. After designing a
Chia-Chia Lee et al.
DNA repair, 9(10), 1073-1079 (2010-08-11)
Deoxyinosine (dI) in DNA can arise from hydrolytic or nitrosative deamination of deoxyadenosine. It is excised in a repair pathway that is initiated by endonuclease V, the nfi gene product, in Escherichia coli. Repair was studied in vitro using M13mp18
Nobuyuki Horinouchi et al.
Applied microbiology and biotechnology, 71(5), 615-621 (2005-11-12)
2'-Deoxyribonucleosides are important as building blocks for the synthesis of antisense drugs, antiviral nucleosides, and 2'-deoxyribonucleotides for polymerase chain reaction. The microbial production of 2'-deoxyribonucleosides from simple materials, glucose, acetaldehyde, and a nucleobase, through the reverse reactions of 2'-deoxyribonucleoside degradation
Susen Hartmann et al.
Clinical chemistry, 52(6), 1127-1137 (2006-04-15)
Clinical presentation and disease severity in disorders of purine and pyrimidine metabolism vary considerably. We present a method that allows comprehensive, sensitive, and specific diagnosis of the entire spectrum of abnormalities in purine and pyrimidine metabolism in 1 analytical run.
Kok Seong Lim et al.
Nature protocols, 1(4), 1995-2002 (2007-05-10)
Several studies examining DNA deamination have published levels of 2'-deoxyinosine that illustrated a large variation between studies. Most of them are the result of artifactual DNA deamination that occurs during the process of sample preparation, particularly acid hydrolysis. This protocol
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