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Sigma-Aldrich

cis-Dichlorobis(dimethyl sulfoxide)platinum(II)

97%

Sinonimo/i:

cis-Dichlorobis(dimethylsulfoxido)platinum(II), Pt(DMSO)2Cl2

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250 MG
CHF 92.90
1 G
CHF 302.00

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250 MG
CHF 92.90
1 G
CHF 302.00

About This Item

Formula empirica (notazione di Hill):
C4H12Cl2O2PtS2
Numero CAS:
Peso molecolare:
422.25
Numero MDL:
Codice UNSPSC:
12161600
ID PubChem:
NACRES:
NA.22

CHF 92.90


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Livello qualitativo

Saggio

97%

Stato

solid

Impiego in reazioni chimiche

core: platinum
reagent type: catalyst

Punto di fusione

218-224 °C

Stringa SMILE

Cl[Pt]Cl.CS(C)=O.CS(C)=O

InChI

1S/2C2H6OS.2ClH.Pt/c2*1-4(2)3;;;/h2*1-2H3;2*1H;/q;;;;+2/p-2
KDADQDWVKZJTDQ-UHFFFAOYSA-L

Descrizione generale

cis-Dichlorobis(dimethyl sulfoxide)platinum(II) is a platinum complex used as a catalyst in various chemical reactions, including the methylation of polyfluorinated aryl imines and methane oxidation. It is identified as an effective C-F activation precatalyst. [1] [2]

Applicazioni

cis-Dichlorobis(dimethyl sulfoxide)platinum(II) can be used as a:
  • Catalyst in the oleum-mediated (SO3-H2SO4) methane oxidation to form methyl bisulfate (MBS). [1]
  • Precursor in the synthesis of cyclometalated complexes. [3]

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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In hepatocellular carcinoma cell lines, the intensity of staining with the monoclonal antibody C-219 to the multidrug-resistant gene (mdr1) product P-glycoprotein and the intensity of the band at a molecular weight of 170 KDa on Western blot were associated closely
J A Gondal et al.
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The systemic toxicity and efficacy of cisplatin (CDDP) were examined in vitro and in vivo. Procedures were performed before and after the antineoplastic agent was encapsulated into multilamellar liposomes (L-CDDP). In vitro cytotoxicity evaluation in L1210 murine leukaemia and NIH
H Nakagawa et al.
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Parenchymal brain tumors, which were metastases of primary lung cancer, were surgically removed from 25 patients. During the operation, patients were administered (intravenous or intracarotid) 100 mg/sq m of cis-diamminedichloroplatinum (CDDP) and postoperatively, they received intravenous CDDP at 3-month intervals
A W Konings et al.
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cDDP-resistant Ehrlich ascites tumour (EAT) cells (ER cells) were tested for cellular content of total glutathione, heat sensitivity, cDDP sensitivity and synergistic effects of a combined treatment of heat and chemotherapy. In comparison with the non-resistant EAT cells (EN) the
L Türkeri et al.
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Traditional approaches for the treatment of locally advanced bladder tumours may not be sufficient enough. Neoadjuvant chemotherapy, a new modality, may be beneficial by enhancing the local and systemic control of the disease. The background of this new modality and

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