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753084

Sigma-Aldrich

Poly(ethylene glycol) diamine

average MN 2,000, cross-linking reagent carboxyl reactive, amine

Sinonimo/i:

Poly(ethylene glycol) bis(amine), Polyethylene glycol, O,O′-Bis(2-aminoethyl)polyethylene glycol, Diaminopolyethylene glycol, PEG-diamine, Polyoxyethylene bis(amine)

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About This Item

Formula condensata:
H2N(CH2CH2O)nCH2CH2NH2
Numero CAS:
24991-53-5
Numero MDL:
MFCD00132004
Codice UNSPSC:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) diamine, average Mn 2,000

Forma fisica

powder

PM

Mw/Mn ≤1.4
average Mn 2,000

Impiego in reazioni chimiche

reagent type: cross-linking reagent
reactivity: carboxyl reactive

Estremità Ω

amine

Estremità α

amine

Architettura del polimero

shape: linear
functionality: homobifunctional

InChI

1S/C6H16N2O2/c7-1-3-9-5-6-10-4-2-8/h1-8H2
IWBOPFCKHIJFMS-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Poly(ethylene glycol) diamine (PEGD) is a non-toxic biopolymer which has properties such as biocompatibility and biodegradability. It can be reacted with crosslinking agents to form a three dimensional mesh that can be used in drug delivery systems. It can also be used as a non-ionic surfactant for a variety of biological applications.

Applicazioni

PEGD can be used as a crosslinked hydrogel and as a substrate in tissue engineering and biomedical applications.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Biodegradable poly (ethylene glycol) hydrogels crosslinked with genipin for tissue engineering applications
Moffat KL and Marra KG
Journal of Biomedical Materials Research. Part B, Applied Biomaterials, 71(1), 181-187 (2004)
Thermal and kinetic evaluation of biodegradable thermo-sensitive gelatin/poly (ethylene glycol) diamine crosslinked citric acid hydrogels for controlled release of tramadol
Rocha-Garcia D, et al.
European Polymer Journal, 89, 42-56 (2017)
Glass surfaces grafted with high-density poly (ethylene glycol) as substrates for DNA oligonucleotide microarrays
Schlapak R, et al.
Langmuir, 22(1), 277-285 (2006)
Rigidity of two-component hydrogels prepared from alginate and poly (ethylene glycol)- diamines
Eiselt P, et al.
Macromolecules, 32(17), 5561-5566 (1999)
Conjugate addition reactions combined with free-radical cross-linking for the design of materials for tissue engineering
Elbert DL and Hubbell JA
Biomacromolecules, 2(2), 430-441 (2001)
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Articoli

Poly(ethylene glycol) (PEG) and Synthetic PEG Derivatives for Tissue Engineering and Cell Delivery

Highlighting new synthetic modifications of PEG to improve the mechanical properties and degradation of resulting hydrogels in tissue engineering applications.

Injectable Hydrogels for Tissue Regeneration

Hydrogel-based biomaterials for cell delivery and tissue regeneration applications are discussed.

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