569755

Hoveyda-Grubbs Catalyst^® M720

Umicore, 97%

• Sinonimo/i: Hoveyda-Grubbs Catalyst^® 2nd Generation, Hoveyda-Grubbs Catalyst^® M72 (C627), (1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium, Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](2-isopropoxyphenylmethylene)ruthenium(II), Grubbs Catalyst^® C627
• Formula empirica (notazione di Hill): C₃₁H₃₈Cl₂N₂ORu
• Numero CAS: 301224-40-8
• Peso molecolare: 626.62
• Numero MDL: MFCD03701614
• Codice UNSPSC: 12161600
• ID PubChem: 24880520
• NACRES: NA.22

Proprietà

• Livello qualitativo: 100
• Saggio: 97%
• Stato: solid
• Impiego in reazioni chimiche: core: ruthenium; reagent type: catalyst; reaction type: Ring-Opening Polymerization
• Punto di fusione: 216-220 °C (lit.)
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: CC(C)Oc1ccccc1C=[Ru](Cl)(Cl)=C2N(CCN2c3c(C)cc(C)cc3C)c4c(C)cc(C)cc4C
• InChI: 1S/C21H26N2.C10H12O.2ClH.Ru/c1-14-9-16(3)20(17(4)10-14)22-7-8-23(13-22)21-18(5)11-15(2)12-19(21)6;1-8(2)11-10-7-5-4-6-9(10)3;;;/h9-12H,7-8H2,1-6H3;3-8H,1-2H3;2*1H;/q;;;;+2/p-2; ZRPFJAPZDXQHSM-UHFFFAOYSA-L

Descrizione

Applicazioni

It′s a phosphine free version of Grubbs 2^nd Generation Catalyst with comparable reactivity, but initiates more readily at lower temperatures. Efficient for metathesis of electron-deficient substrates including fluorinated olefins. Demonstrated in multiple large-scale pharmaceutical applications.
It can be used as a catalyst for olefin cross-metathesis with fluorinated olefins (CM),[1] ring-closing metathesis (RCM),[2] ring-opening metathesis (ROM),[3] and a sequence of a metathesis reaction and subsequent dihydroxylation of the newly formed double bond.[4]

Learn more about our metathesis catalysts

Altre note

Grubbs Catalyst^® Technology for Olefin Metathesis by Aldrich

Note legali

Product of Umicore

Product License
This product, its manufacturing or use, is the subject of one or more issued or pending U.S. Patents (and foreign equivalents) owned or controlled by Umicore PMC. The purchase of this product from Umicore PMC through Sigma-Aldrich, its affiliates or their authorized distributors conveys to the buyer a limited, one-time, non-exclusive, non-transferable, non-assignable license. Buyer′s use of this product may infringe patents owned or controlled by third parties. It is the sole responsibility of buyer to ensure that its use of the product does not infringe the patent rights of third parties or exceed the scope of the license granted herein.

For any further information on product please refer to your local Umicore PMC contact at http://www.pmc.umicore.com

Grubbs Catalyst is a registered trademark of Umicore AG & Co. KG

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)