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293040

Sigma-Aldrich

Ossido di deuterio

99.9 atom % D, contains 0.75 wt. % 3-(trimethylsilyl)propionic-2,2,3,3-d4 acid, sodium salt

Sinonimo/i:

Acqua pesante, Acqua-d2

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About This Item

Formula empirica (notazione di Hill):
D2O
Numero CAS:
7789-20-0
Peso molecolare:
20.03
Numero CE:
232-148-9
Numero MDL:
MFCD00044636
Codice UNSPSC:
12142201
ID PubChem:
24857630
NACRES:
NA.21
Prezzi e disponibilità al momento non sono disponibili

Purezza isotopica

99.9 atom % D

Livello qualitativo

100

Stato

liquid

contiene

0.75 wt. % 3-(trimethylsilyl)propionic-2,2,3,3-d4 acid, sodium salt

tecniche

NMR: suitable

P. ebollizione

101.4 °C (lit.)

Punto di fusione

3.8 °C (lit.)

Stringa SMILE

[2H]O[2H]

InChI

1S/H2O/h1H2/i/hD2
XLYOFNOQVPJJNP-ZSJDYOACSA-N

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Categorie correlate

Applicazioni


  • Analgesic biochemical research: Hydromorphone is used in biochemical research to assess its analgesic potency and side effects, providing insights into its therapeutic window and safety profile. This research supports the development of safer pain management strategies (Zimbelmann et al., 2024).


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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
MKCX2063
MKCX1985
MKCW5489
MKCW5490
MKCV9147

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Sigma-Aldrich

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Deuterium oxide deuteration degree min. 99.9% for NMR spectroscopy MagniSolv™

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Deuterium oxide

The ionization constant of deuterium oxide from 5 to 50?.
Covington AK, et al.
The Journal of Physical Chemistry, 70(12), 3820-3824 (1966)
Structure of water and hydrophobic bonding in proteins. IV. The thermodynamic properties of liquid deuterium oxide.
Nemethy G and Scheraga HA.
J. Chem. Phys. , 41(3), 680-689 (1964)
Using high-performance quantitative NMR (HP-qNMR?) for certifying traceable and highly accurate purity values of organic reference materials with uncertainties< 0.1%.
Weber M, et al.
Accreditation and Quality Assurance, 18(2), 91-98 (2013)
Lars Holm et al.
American journal of physiology. Endocrinology and metabolism, 304(8), E895-E907 (2013-02-21)
A method to determine the rate of protein breakdown in individual proteins was developed and tested in rats and confirmed in humans, using administration of deuterium oxide and incorporation of the deuterium into alanine that was subsequently incorporated into body
Takhar Kasumov et al.
American journal of physiology. Heart and circulatory physiology, 304(9), H1201-H1214 (2013-03-05)
Traditional proteomics provides static assessment of protein content, but not synthetic rates. Recently, proteome dynamics with heavy water ((2)H2O) was introduced, where (2)H labels amino acids that are incorporated into proteins, and the synthesis rate of individual proteins is calculated
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Questions

1–2 of 2 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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