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182028

Sigma-Aldrich

Poli(etilene ossido)

average MV 600,000 (nominal), powder, hydroxyl, BHT as inhibitor

Sinonimo/i:

PEO

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About This Item

Formula condensata:
(-CH2CH2O-)n
Numero CAS:
25322-68-3
Numero MDL:
MFCD00081839
Codice UNSPSC:
12352104
ID PubChem:
24850972
NACRES:
NA.23
Prezzi e disponibilità al momento non sono disponibili

Nome del prodotto

Poli(etilene ossido), average Mv 600,000 (nominal), powder

Stato

powder

Livello qualitativo

100

PM

average Mv 600,000 (nominal)

contiene

200-500 ppm BHT as inhibitor

Viscosità

4,500-8,800 cP, 5 % in H2O(25 °C, Brookfield)(lit.)

Temp. transizione

Tm 65 °C

Estremità Ω

hydroxyl

Estremità α

hydroxyl

applicazioni

battery manufacturing

Stringa SMILE

[H]OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Poly(ethylene oxide)(PEO) is a high molecular weight, non-ionic water-soluble polymer. It forms agel on hydration and shows good swelling capacity. PEO polymers are non-toxicand widely used in drug delivery systems to enhance drug solubility.

Applicazioni

Poly(ethylene oxide) can be used to prepare:
  • Bioabsorbable and injectable hydrogels for sustained drug release.
  • PEO/graphene oxide composite electrolyte membrane for fuel cells.
  • Poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO-b-PCL) diblock copolymer. Losartan potassium encapsulated (PEO-b-PCL) copolymer can be used as a drug carrier.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
0000372775
0000305695
MKCW1590
MKCV6006
MKCW1008

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1 of 8

Poli(etilenglicole) United States Pharmacopeia (USP) Reference Standard

USP

1546853

Poli(etilenglicole)

Poli(etilenglicole) analytical standard

Supelco

02393

Poli(etilenglicole)

Poli(etilenglicole) 35,000

Sigma-Aldrich

81310

Poli(etilenglicole)

Lithium trifluoromethanesulfonate 99.995% trace metals basis

Sigma-Aldrich

481548

Lithium trifluoromethanesulfonate

Lithium perchlorate 99.99% trace metals basis

Sigma-Aldrich

431567

Lithium perchlorate

Succinonitrile 99%

Sigma-Aldrich

160962

Succinonitrile

Bis(trifluorometano)sulfonimide 99.95% trace metals basis

Sigma-Aldrich

544094

Bis(trifluorometano)sulfonimide

Poli(etilenglicole) average Mn 6,000

Sigma-Aldrich

81260

Poli(etilenglicole)

Jun Li et al.
Journal of biomedical materials research. Part A, 65(2), 196-202 (2003-05-08)
Polymeric hydrogels long have attracted interest for biomaterials applications because of their generally favorable biocompatibility. High in water content, they are particularly attractive for delivery of delicate bioactive agents, such as proteins. However, because they require covalent crosslinking for gelation
Angeliki Chroni et al.
Nanomaterials (Basel, Switzerland), 10(9) (2020-09-24)
We report on the preparation of drug nanocarriers by encapsulating losartan potassium (LSR) into amphiphilic block copolymer micelles, utilizing the biocompatible/biodegradable poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO-b-PCL) diblock copolymer. The PEO-b-PCL micelles and LSR-loaded PEO-b-PCL nanocarriers were prepared by organic solvent evaporation method
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
M Patel Geeta et al.
Current drug delivery, 6(2), 159-165 (2009-05-20)
Carbamazepine indicated for the control of epilepsy, undergoes extensive hepatic first-pass metabolism after oral administration. A vaginal dosage form of carbamazepine is not commercially available. Conventional suppository having poor retention in the vaginal tract, as they are removed in a
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Articoli

Electrospinning: Enabling Nanostructured Materials

Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds: Bio-orthogonal Click

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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