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145904

Sigma-Aldrich

Quinine

90%

Sinonimo/i:

6′-Methoxycinchonidine

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CHF 64.70
50 G
CHF 223.00

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10 G
CHF 64.70
50 G
CHF 223.00

About This Item

Formula empirica (notazione di Hill):
C20H24N2O2
Numero CAS:
Peso molecolare:
324.42
Beilstein:
91867
Numero CE:
Numero MDL:
Codice UNSPSC:
12352104
ID PubChem:
NACRES:
NA.22

CHF 64.70


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Saggio

90%

Attività ottica

[α]25/D −165°, c = 2 in ethanol

Punto di fusione

173-175 °C (lit.)

Gruppo funzionale

hydroxyl

Stringa SMILE

COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1

InChI

1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1
LOUPRKONTZGTKE-WZBLMQSHSA-N

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Descrizione generale

Quinine, a cinchona alkaloid found in the bark of the cinchona tree, is known for its anti-malarial property.[1]

Applicazioni

Quinine has been used as a standard during the chemical evaluation of alkaloids in the hydroethanolic extracts of endophytic fungi obtained from the leaves of Costus spiralis by TLC.[2]
Resolving agent for carboxylic acids.[3] Catalyzes the kinetic resolution of furanones.[4]

Azioni biochim/fisiol

Potassium channel blocker

Altre note

remainder hydroquinine

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Chemical assessment and antimicrobial and antioxidant activities of endophytic fungi extracts isolated from Costus spiralis (Jacq.) Roscoe (Costaceae)
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Chirality, 4, 323-323 (1992)
Tetrahedron, 50, 4775-4775 (1994)
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Exchange transfusion (ET) has remained a controversial adjunct therapy for the treatment of severe malaria. In order to assess the relative contribution of ET to parasite clearance in severe malaria, all patients receiving ET as an adjunct treatment to parenteral
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Journal of medicinal chemistry, 49(8), 2417-2430 (2006-04-14)
Automated docking strategies successfully applied to binding mode predictions of ligands in Cyt P450 crystal structures in an earlier study (de Graaf et al. J. Med. Chem. 2005, 7, 2308-2318) were used for the catalytic site prediction (CSP) of 65

Questions

1–3 of 3 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. What is the Flinn compatibility storage code and the storage condition for product 145904?

    1 answer
    1. Product 145904 should be stored at ambient temperature in a dark place due to its light sensitivity. The Flinn compatibility storage code (TRGS 510) for this item is 11, indicating it is a combustible solid.

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