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129925

Sigma-Aldrich

Methyl methanesulfonate

99%

Sinonimo/i:

Methanesulfonic acid methyl ester

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About This Item

Formula condensata:
CH3SO3CH3
Numero CAS:
66-27-3
Peso molecolare:
110.13
Beilstein:
1098586
Numero CE:
200-625-0
Numero MDL:
MFCD00007557
Codice UNSPSC:
12352103
ID PubChem:
24847934
NACRES:
NA.22

Livello qualitativo

100

Saggio

99%

Forma fisica

liquid

Indice di rifrazione

n20/D 1.414 (lit.)

P. eboll.

202-203 °C (lit.)

Densità

1.3 g/mL at 25 °C (lit.)

Stringa SMILE

COS(C)(=O)=O

InChI

1S/C2H6O3S/c1-5-6(2,3)4/h1-2H3
MBABOKRGFJTBAE-UHFFFAOYSA-N

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Principio

DNA adduct; adds methyl groups to DNA at 7-guanine preferentially, but also 3-adenine and 3-guanine.

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Inhalation

Organi bersaglio

Lungs

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

219.2 °F - closed cup

Punto d’infiammabilità (°C)

104 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificati d'analisi (COA)

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Sigma-Aldrich

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Sigma-Aldrich

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Sigma-Aldrich

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Amaya Azqueta et al.
Toxicology in vitro : an international journal published in association with BIBRA, 27(2), 768-773 (2012-12-25)
A serious limitation of the conventional comet assay (single cell gel electrophoresis) is the restriction on the number of samples that can be processed in one experiment, imposed by the size of the electrophoresis platform. One approach to increasing throughput
Cathrine Broberg Vågbø et al.
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Cytotoxic 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) lesions induced in DNA and RNA in vitro and in pre-damaged DNA and RNA bacteriophages in vivo are repaired by the Escherichia coli (E. coli) protein AlkB and a human homolog, ALKBH3. However, it
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Nucleic acids research, 41(8), 4525-4534 (2013-03-06)
The Saccharomyces cerevisiae Shu complex, consisting of Shu1, Shu2, Csm2 and Psy3, promotes error-free homologous recombination (HR) by an unknown mechanism. Recent structural analysis of two Shu proteins, Csm2 and Psy3, has revealed that these proteins are Rad51 paralogues and
R Santos et al.
Reproductive toxicology (Elmsford, N.Y.), 36, 6-11 (2012-11-28)
Many xenobiotics released in the aquatic environment exhibit a genotoxic potential toward organisms. Long term exposure to such compounds is expected to lead to multigenerational reproductive defects, further influencing the recruitment rate and hence, the population dynamics. Paternal exposure to
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Proceedings of the National Academy of Sciences of the United States of America, 110(39), 15842-15847 (2013-09-11)
Observing cellular responses to perturbations is central to generating and testing hypotheses in biology. We developed a massively parallel microchemostat array capable of growing and observing 1,152 yeast-GFP strains on the single-cell level with 20 min time resolution. We measured
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