T0557

Natriumtaurodesoxycholat Hydrat

BioXtra, ≥97% (TLC)

• Synonym(e): 2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]-amino)-ethansulfonsäure, Taurodeoxycholsäure Natriumsalz Hydrat
• Lineare Formel: C₂₆H₄₄NO₆SNa · xH₂O
• CAS-Nummer: 207737-97-1
• Molekulargewicht: 521.69 (anhydrous basis)
• Beilstein: 3901204
• MDL-Nummer: MFCD00149238
• UNSPSC-Code: 12161900
• PubChem Substanz-ID: 24899897
• NACRES: NA.25

Eigenschaften

• Beschreibung: anionic
• Produktlinie: BioXtra
• Assay: ≥97% (TLC)
• Mol-Gew.: micellar avg mol wt 3100
• Aggregatnummer: 6
• Verunreinigungen: ≤0.002% Phosphorus (P); ≤0.1% Insoluble matter
• CMC: 1-4 mM (20-25°C)
• Löslichkeit: H₂O: 0.5 M, clear, colorless to faintly yellow
• Anionenspuren: chloride (Cl^-): ≤0.5%; sulfate (SO₄^2-): ≤0.05%
• Kationenspuren: Al: ≤0.0005%; Ca: ≤0.005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.01%; Mg: ≤0.005%; NH₄⁺: ≤0.05%; Pb: ≤0.001%; Zn: ≤0.0005%
• SMILES String: O.[Na+].C[C@H](CCC(=O)NCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
• InChI: 1S/C26H45NO6S.Na.H2O/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3;;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);;1H2/q;+1;/p-1/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-;;/m1../s1
• InChIKey: OLPIZAYYAVQETM-GGPRKOIFSA-M

Beschreibung

Allgemeine Beschreibung

Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.

Anwendung

Sodium tauroursodeoxycholate has been used in a study to assess short-term feedback regulation of bile salt uptake in rodent liver. It has also been used in a study to investigate its potential to resolve endoplasmic reticulum (ER) stress in intestinal epithelial cells. It is also used for isolation of membrane proteins including inner mitochondrial membrane proteins.

Zu den Gallensalzen gehörendes anionisches Detergens, das zur Isolierung von Membranproteinen verwendet wird, einschließlich Proteinen der inneren mitochondrialen Membran.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)