SML3099

Glyght

≥95% (HPLC)

• Synonym(e): (E)-5-Phenyl-7-(pyridin-2-yldiazenyl)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
• Empirische Formel (Hill-System): C₂₀H₁₅N₅O
• CAS-Nummer: 2505025-38-5
• Molekulargewicht: 341.37
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: powder
• Lagerbedingungen: protect from light at room temperature
• Farbe: yellow to orange
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: O=C1NC(C=CC(/N=N/C2=NC=CC=C2)=C3)=C3C(C4=CC=CC=C4)=NC1
• InChI: 1S/C20H15N5O/c26-19-13-22-20(14-6-2-1-3-7-14)16-12-15(9-10-17(16)23-19)24-25-18-8-4-5-11-21-18/h1-12H,13H2,(H,23,26)/b25-24+
• InChIKey: MQMSSOZUTXPEIC-OCOZRVBESA-N

Beschreibung

Allgemeine Beschreibung

Glyght is a benzodiazepine-containing azobenzene compound that acts as a light-controlled negative allosteric modulator that is selective to glycine receptors. It is a powerful and effective compound that can operate in vivo. Glyght attaches to an allosteric site within the interface between the extracellular and transmembrane domains.[1] It is an effective tool for researchers since it has broad activity in both homo- and heteromeric GlyRs across several species of fish and mammals. Moreover, Glyght is photo-switchable at 365 nm for trans-cis isomerization and 455 to 530 nm for cis-trans isomerization.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable