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SAB5700739

Sigma-Aldrich

Anti-TGFBR2 antibody produced in rabbit

Synonym(e):

AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TGF beta Receptor II, TGFBR2, TGFR-2, TGFbeta-RII

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100 μL
CHF 365.00

CHF 365.00


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100 μL
CHF 365.00

About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

CHF 365.00


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Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

64
67

Speziesreaktivität

rat, human, mouse

Konzentration

1.92 mg/ml

Methode(n)

immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... TGFBR2(7048)

Allgemeine Beschreibung

This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 23-280 of human TGFBR2 (NP_003233.4).

Physikalische Form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Lagerung und Haltbarkeit

Store at -20℃. Avoid freeze / thaw cycles.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Questions

  1. Could Product No. SAB5700739, Anti-TGFBR2 antibody, result in a cross reaction with bovine?

    1 answer
    1. The antibody SAB5700739 has not been specifically tested for cross reaction with bovine. Nevertheless, it's worth noting that there is a 95% homology of the immunogen used to produce the antibody with Bovine TGFBR2 (UniProt E1B702). Generally, with polyclonal antibodies, if there is greater than 85% homology between the protein and the immunogen used to produce the antibody, there is a likelihood of cross reaction.

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