The antibody E1-2.5 recognizes repetitive Gly-Ala region of the Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA-1). EBNA-1 is the only viral protein consistently expressed in all malignancies associated with EBV.
Immunogen
EBNA-1
Biochem./physiol. Wirkung
Epstein–Barr nuclear antigen 1 (EBNA-1) plays an essential role in the replication of the Epstein-Barr virus (EBV) genome as an extrachromosomal element. In addition, it also regulates transcription of a EBV latent gene expression. EBNA-1 is essential for maintenance of EBV in episomal form.
Leistungsmerkmale und Vorteile
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Physikalische Form
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Antibody responses to Epstein-Barr virus-determined nuclear antigen (EBNA)-1 and EBNA-2 in acute and chronic Epstein-Barr virus infection
Henle W, et al.
Proceedings of the National Academy of Sciences of the USA, 84(2), 570-574 (1987)
EBNA?1: a protein pivotal to latent infection by Epstein?Barr virus
Leight ER, et al.
Reviews in Medical Virology, 10(2), 83-100 (2000)
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