Hantaan virus (HNTV) is the prototype virus of the genus hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA virus that is the eiological agent of Korean hemorrhagic fever. Infection of cultured Vero E6 cells with HNTV induced expression of the heat shock protein HSP70. A substantial fraction of HSP70 was found to be associated with the HNTV nucleocapsid (NP). Vero E6 cells that overexpress HSP70 show significantly reduced levels of NP and an increased resistance to infection by HNTV.
Immunogen
Hantaan virus nucleocapsid antibody was raised against an 18 amino acid peptide near the amino terminus of the Hantaan virus nucleocapsid.The immunogen is located within the first 50 amino acids of Hantaan Virus Nucleocapsid.
Anwendung
Hantaan virus nucleocapsid antibody can detect 10ng Hantaan virus nucleocapsid peptide in ELISA at 1 μg/ml.
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