T-cells stimulated with SEB produce high levels of IFN-γ, while PHA-stimulated T-cells produce little or no IFN-γ. For more information, refer to the reference at the following link: https://pmc.ncbi.nlm.nih.gov/articles/PMC1906565/#:~:text=%2Dcells%20(Fig.-,1).,compared%20to%20CD4+%20T%2Dcells
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S4881
Staphylokokken-Enterotoxin B aus Staphylococcus aureus
Synonym(e):
Enterotoxin B, von Staphylokokken, SEB
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1 MG
CHF 338.00
5 MG
CHF 1’340.00
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1 MG
CHF 338.00
5 MG
CHF 1’340.00
About This Item
Empfohlene Produkte
Enthält
sodium phosphate buffer as balance
Qualitätsniveau
Zusammensetzung
Protein, ~25% Lowry
Verfügbarkeit
not available in USA
Verunreinigungen
Staphylococcal enterotoxin A (SEA), essentially free
Anwendung(en)
metabolomics
vitamins, nutraceuticals, and natural products
Lagertemp.
2-8°C
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Anwendung
Staphylokokken-Enterotoxin-B (SEB) bindet an MHC-Moleküle der Klasse II und an spezifische Vβ-Regionen von T-Zell-Rezeptoren (TCR) und aktiviert sowohl Monozyten/Makrophagen also auch T-Lymphozyten. SEB kann als Superantigen und als Aktivator des Immunsystems verwendet werden. In der Entwicklung von SEB-Nachweissystemen kann SEB als Referenzmaterial genutzt werden.
Biochem./physiol. Wirkung
Verpackung
Packungsgröße basiert auf dem Proteingehalt.
Ähnliches Produkt
Produkt-Nr.
Beschreibung
Preisangaben
Signalwort
Danger
Gefahreneinstufungen
Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Analysenzertifikate (COA)
Lot/Batch Number
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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.
Bacterial superantigens
Proft, T. and Fraser, J.D.
Clinical and Experimental Immunology, 133, 299-299 (2008)
Clarifying the mechanism of superantigen toxicity.
John D Fraser
PLoS biology, 9(9), e1001145-e1001145 (2011-09-21)
Winnie Bergstedt et al.
PloS one, 5(6), e11277-e11277 (2010-07-02)
Tuberculin is still the only available skin test reagent for the diagnosis of mycobacterial infection. The product has a remarkable sensitivity, but poor specificity. Previous studies, including two human phase I clinical trials, have indicated that rdESAT-6 has a potential
Oliver G Weingart et al.
Sensors (Basel, Switzerland), 12(2), 2324-2339 (2012-03-23)
Prevalent incidents support the notion that toxins, produced by bacteria, fungi, plants or animals are increasingly responsible for food poisoning or intoxication. Owing to their high toxicity some toxins are also regarded as potential biological warfare agents. Accordingly, control, detection
Philippe O Gannon et al.
Cytotherapy, 22(12), 780-791 (2020-10-19)
Several studies report on Good Manufacturing Process (GMP)-compliant manufacturing protocols for the ex vivo expansion of tumor-infiltrating lymphocytes (TILs) for the treatment of patients with refractory melanoma and other solid malignancies. Further opportunities for improvements in terms of ergonomy and
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What is the difference in effects on T-lymphocyte proliferation between PHA and SEB? Thank you
1 answer-
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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こんにちは、この商品の容量をお聞きしたいのですが、1MGと表記されている場合、1miligramということでしょうか？ 溶かしてから調剤したいのですが。 溶かして調剤する際のプロトコルはあるのでしょうか？
1 answer-
Yes, the 1MG does stand for one milligram. The product is soluble in water at 4 mg/ml. It may also be dissolved in an aqueous buffer such as PBS. See the link below to the product information sheet for additional solution stability information:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/126/857/s4881pis.pdfHelpful?
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