P0359

Palmitoylethanolamide

≥98% (HPLC), powder, cannabinoid receptor agonist

• Synonym(e): N-(2-Hydroxyethyl)hexadecanamide, PEA, Palmidrol
• Empirische Formel (Hill-System): C₁₈H₃₇NO₂
• CAS-Nummer: 544-31-0
• Molekulargewicht: 299.49
• EG-Nummer: 208-867-9
• MDL-Nummer: MFCD00020562
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24278619
• NACRES: NA.77

Eigenschaften

• product name: Palmitoylethanolamide,
• Form: powder
• Lagertemp.: −20°C
• SMILES String: CCCCCCCCCCCCCCCC(=O)NCCO
• InChI: 1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
• InChIKey: HXYVTAGFYLMHSO-UHFFFAOYSA-N
• Angaben zum Gen: human ... CNR1(1268) , CNR2(1269) ; rat ... Faah(29347)

Beschreibung

Anwendung

Palmitoylethanolamide has been used as a reference standard in mass spectrometry (MS/MS).

Biochem./physiol. Wirkung

Palmitoylethanolamide (PEA) is a natural fatty acid amide of ethanolamine and palmitic acid. It is found in soybeans, egg yolk, and many other food sources. PEA is an endogenous cannabinoid receptor agonist. It is a peroxisome proliferator-activated receptor α (PPAR-α) ligand. PEA possesses anti-inflammatory, anti-allergic, neuroprotective, and analgesic activities. It belongs to the class of lipid mediators and the N-acylethanolamine family. PEA blocks the release of pro-inflammatory mediators from activated mast cells and prevents the recruitment of activated mast cells at the site of nerve injury.

Verlinkung

Structural analog of anandamide.

Sicherheitshinweise

• Piktogramme: GHS05,GHS09
• Signalwort: Danger
• H-Sätze: H315,H318,H411
• P-Sätze: P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Gefahreneinstufungen: Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)