Product O9389, Oltipraz, has no Retest or Expiration Date. There are a number of products with the only date shown on the lot-specific Certificate of Analysis being the Release Date. For these products there is no stated Retest, Expiration or Use-by-Date Date. We recommend handling per defined conditions as printed in our product literature and website product descriptions. Products should be routinely inspected by the customer to ensure they perform as expected.
For those products, only our standard warranty of 1 year is applicable. For further information on our warranty please refer to terms and conditions of sale.
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Wichtige Dokumente
O9389
Oltipraz
≥98% (HPLC), powder
Synonym(e):
4-Methyl-5-(2-pyrazinyl)-1,2-dithiole-3-thione, BRN 0978110, CCRIS 4048, NSC 347901, RP 35972
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5 MG
CHF 103.00
25 MG
CHF 415.00
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5 MG
CHF 103.00
25 MG
CHF 415.00
About This Item
Empirische Formel (Hill-System):
C8H6N2S3
CAS-Nummer:
Molekulargewicht:
226.34
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352200
PubChem Substanz-ID:
NACRES:
NA.77
Empfohlene Produkte
Qualitätsniveau
Assay
≥98% (HPLC)
Form
powder
Lagerbedingungen
protect from light
Farbe
red
Löslichkeit
DMSO: >20 mg/mL
Lagertemp.
2-8°C
SMILES String
CC1=C(SSC1=S)c2cnccn2
InChI
1S/C8H6N2S3/c1-5-7(12-13-8(5)11)6-4-9-2-3-10-6/h2-4H,1H3
InChIKey
CKNAQFVBEHDJQV-UHFFFAOYSA-N
Allgemeine Beschreibung
Biochem./physiol. Wirkung
Oltipraz is an activator of Nrf2.
Oltipraz is an activator of Nrf2. Nrf2 (NF-E2-related factor 2) is a transcription factor that binds to antioxidant response elements (AREs) and activates these genes. Oltipraz activates Nrf2 and subsequently elevates expression of the detoxification genes encoding anti-oxidant and multidrug resistance-associated proteins to mediate its chemopreventive efficacy.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
dust mask type N95 (US), Eyeshields, Gloves
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The transcription factor NF-E2 p45-related factor 2 (NRF2; encoded by NFE2L2) plays a critical role in the maintenance of cellular redox and metabolic homeostasis, as well as the regulation of inflammation and cellular detoxication pathways. The contribution of the NRF2
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