I0661

(−)-Indolactam V

≥96% (HPLC)

• Synonym(e): (2S,5S)-1,2,4,5,6,8-Hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonin-3-one
• Empirische Formel (Hill-System): C₁₇H₂₃N₃O₂
• CAS-Nummer: 90365-57-4
• Molekulargewicht: 301.38
• MDL-Nummer: MFCD00151197
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329815323
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥96% (HPLC)
• Form: powder
• Farbe: white
• Lagertemp.: −20°C
• SMILES String: CC(C)[C@@H]1N(C)c2cccc3[nH]cc(C[C@@H](CO)NC1=O)c23
• InChI: 1S/C17H23N3O2/c1-10(2)16-17(22)19-12(9-21)7-11-8-18-13-5-4-6-14(15(11)13)20(16)3/h4-6,8,10,12,16,18,21H,7,9H2,1-3H3,(H,19,22)/t12-,16-/m0/s1
• InChIKey: LUZOFMGZMUZSSK-LRDDRELGSA-N

Beschreibung

Biochem./physiol. Wirkung

(-)-Indolactam V is a PKC activator shown to effect differentiation in embryonic stem cells leading to development of pancreatic precursors.

(-)-Indolactam V is a PKC activator shown to effect differentiation in embryonic stem cells leading to development of pancreatic precursors. It is active in the mouse model.

(−)-Indolactam V is naturally present in Streptoverticillium blastmyceticum.[1] It serves as a precursor to the teleocidin class which are alkaloids.[2] It is a the pharmacophore of lyngbyatoxin[1] and teleocidins.[2]

Leistungsmerkmale und Vorteile

This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable