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G0902

Sigma-Aldrich

Ginsenoside-Rc from Panax ginseng (Korean ginseng) root

triterpenoid saponin, ≥98% (HPLC)

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About This Item

Empirische Formel (Hill-System):
C53H90O22
CAS-Nummer:
11021-14-0
Molekulargewicht:
1079.27
EG-Nummer:
234-253-5
MDL-Nummer:
MFCD00133368
UNSPSC-Code:
12352201
PubChem Substanz-ID:
24895029
NACRES:
NA.25

Biologische Quelle

plant root (Panax ginseng)

Qualitätsniveau

200

Assay

≥98% (HPLC)

Form

powder

Methode(n)

HPLC: suitable

Lagertemp.

2-8°C

SMILES String

C\C(C)=C\CCC(C)(OC1OC(COC2OC(CO)C(O)C2O)C(O)C(O)C1O)C3CCC4(C)C3C(O)CC5C6(C)CCC(OC7OC(CO)C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(C)(C)C6CCC45C

InChI

1S/C53H90O22/c1-23(2)10-9-14-53(8,75-47-43(67)39(63)37(61)29(72-47)22-68-45-41(65)36(60)28(21-56)69-45)24-11-16-52(7)33(24)25(57)18-31-50(5)15-13-32(49(3,4)30(50)12-17-51(31,52)6)73-48-44(40(64)35(59)27(20-55)71-48)74-46-42(66)38(62)34(58)26(19-54)70-46/h10,24-48,54-67H,9,11-22H2,1-8H3

InChIKey

JDCPEKQWFDWQLI-UHFFFAOYSA-N

Biochem./physiol. Wirkung

Ginsenoside-Rc exhibits anti-proliferative effects on human breast cancer cell lines and can induce expreβion of the leucine-zipper transcription factor c-fos.
Triterpene saponin found in ginseng.

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Anwendung

Produkt-Nr.
Beschreibung
Preisangaben

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Young Joo Lee et al.
Archives of pharmacal research, 26(1), 53-57 (2003-02-06)
We have found that ginsenoside Rc and Re induce c-fos in MCF-7 human breast carcinoma cells at both the mRNA and protein levels. However, neither ginsenoside activated the expression of reporter gene under the control of AP-1/TPA response elements. We
T B Ng et al.
Journal of ethnopharmacology, 16(2-3), 191-199 (1986-06-01)
Ginsenosides Rb2, Rc and Rg1 suppressed corticotropin-induced, dibutyryl cyclic AMP-induced and epinephrine-induced lipolysis with the relative potencies Rb2 greater than Rc greater than Rg1. The inhibition of corticotropin-induced lipolysis by ginsenoside Rg1 could not be overcome by increasing the dose
Osamu Morinaga et al.
Glycobiology, 15(10), 1061-1066 (2005-06-24)
A method has been devised for the chromatographic resolution of glucosidic compounds, ginseng saponins, on polyethersulphone (PES) membrane. The method results in good resolution and quantitative immunoassay for ginsenoside Rb1 (G-Rb1), G-Rc, and G-Rd in crude extracts of various ginsengs.
Yang Chu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 919-920, 75-78 (2013-02-16)
Ginsenoside Rc (GRc) is a potential pharmacologically active ingredient isolated from ginseng (Panax ginseng C.A. Meyer, Araliaceae). A simple, rapid and sensitive method for determination of GRc in rat plasma was developed based on liquid chromatography-tandem mass spectrometry (LC-MS/MS). The
Yong-jiang Wu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 30(9), 662-665 (2005-08-04)
To investigate the effect of different preparation method on the quality of Shen-mai injection. The Shen-mai injection samples were prepared using three different methods. Fingerprints of Shen-mai extracts red ginseng, and its intermediates were obtained using an HPLC analytical procedure.
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Chromatograms

application for HPLC

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