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D2510

Deoxycholsäure

≥98% (HPLC)

Synonym(e):

3α,12α-Dihydroxy-5β-cholansäure, 7-Deoxycholsäure, Deoxycholsäure

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PackungsgrößeSKUVerfügbarkeitPreis
10 g
Warenkorb auf Verfügbarkeit prüfen
CHF 48.90
100 g
Warenkorb auf Verfügbarkeit prüfen
CHF 256.00
500 g
Warenkorb auf Verfügbarkeit prüfen
CHF 884.00
CHF 663.00

Über diesen Artikel

Empirische Formel (Hill-System):
C24H40O4
CAS-Nummer:
Molekulargewicht:
392.57
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
EC Number:
201-478-5
Beilstein/REAXYS Number:
3219882
MDL number:

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biological source

bovine bile (ex gall bladder)

Quality Segment

description

anionic

assay

≥98% (HPLC)

form

powder

mol wt

392.57 g/mol

mp

171-174 °C (lit.)

functional group

carboxylic acid

shipped in

ambient

storage temp.

room temp

SMILES string

C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-/m1/s1

InChI key

KXGVEGMKQFWNSR-LLQZFEROSA-N

Gene Information

human ... ATIC(471)

General description

Deoxycholic acid is a proinflammatory agent. [1]

Application

Deoxycholic acid has been used in a study to assess a pH-Responsive Mechanism of a Deoxycholic Acid and Folate Co-Modified Chitosan Micelle under Cancerous Environment. It has also been used in a study to investigate dose-dependent anti-inflammatory effect of ursodeoxycholic acid in experimental colitis. [1]

Biochem/physiol Actions

Bile Acid

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Dieser Artikel
30960PHR3659700197P
form

powder

form

powder

form

-

form

powder

assay

≥98% (HPLC)

assay

≥99.0% (T)

assay

-

assay

99% (TLC)

storage temp.

room temp

storage temp.

-

storage temp.

2-30°C

storage temp.

−20°C

Quality Level

200

Quality Level

100

Quality Level

300

Quality Level

-

description

anionic

description

anionic

description

-

description

-

mp

171-174 °C (lit.)

mp

170-175 °C, 171-174 °C (lit.)

mp

171-174 °C (lit.)

mp

-


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Analysenzertifikate (COA)

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Protokolle

Investigate bile acid roles in gut hormone profiles and glycemic control, vital for clinical labs exploring potential mechanisms.

Verwandter Inhalt

Bile Acids (BA) are synthesized in the liver and play important roles in cholesterol homeostasis, absorption of vitamins and lipids, and various key metabolic processes.

Product Information Sheet

Alle verwandten Inhalte anzeigen

pH-Responsive Mechanism of a Deoxycholic Acid and Folate Co-Modified Chitosan Micelle under Cancerous Environment
Chen, D., et al.
The Journal of Physical Chemistry B, 1261-1268 (2013)
Patricia Martínez-Moya et al.
International immunopharmacology, 15(2), 372-380 (2012-12-19)
The denomination of inflammatory bowel disease comprises a group of chronic inflammatory diseases of the digestive tract, ulcerative colitis and Crohn's disease being the most important conditions. Bile acids may play a role both in etiology and pharmacology of this
Jeffery L Smith et al.
Hepatology (Baltimore, Md.), 39(6), 1673-1682 (2004-06-09)
Focal biliary cirrhosis causes significant morbidity and mortality in cystic fibrosis (CF). Although the mechanisms of pathogenesis remain unclear, bile acids have been proposed as potential mediators of liver injury. This study examined bile acid composition in CF and assessed



Global Trade Item Number

SKUGTIN
D2510-100G04061833562314
D2510-500G04061833562338
D2510-10G04061833562321

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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