C6491

Chrysomycin B

≥98% (HPLC), solid

• Empirische Formel (Hill-System): C₂₇H₂₈O₉
• CAS-Nummer: 83852-56-6
• Molekulargewicht: 496.51
• MDL-Nummer: MFCD07370132
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24892870
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: solid
• Löslichkeit: DMF: soluble; DMSO: soluble; ethanol: moderately soluble; methanol: moderately soluble
• Wirkungsspektrum von Antibiotika: neoplastics
• Wirkungsweise: enzyme | inhibits
• Lagertemp.: 2-8°C
• SMILES String: COc1cc(C)cc2C(=O)Oc3c(cc(OC)c4c(O)ccc([C@@H]5O[C@H](C)[C@H](O)[C@@](C)(O)[C@H]5O)c34)-c12
• InChI: 1S/C27H28O9/c1-11-8-15-19(17(9-11)33-4)14-10-18(34-5)21-16(28)7-6-13(20(21)22(14)36-26(15)31)23-25(30)27(3,32)24(29)12(2)35-23/h6-10,12,23-25,28-30,32H,1-5H3/t12-,23+,24+,25+,27-/m1/s1
• InChIKey: BJPYMDSMDBCKEP-QSMCFSHASA-N

Beschreibung

Biochem./physiol. Wirkung

Antibiotic from Streptomyces sp. Inhibits the catalytic activity of human topoisomerase II.

Antibiotic from Streptomyces sp. Inhibits the catalytic activity of human topoisomerase II. Exhibits antitumor activity against human cell lines K562, HT29, MCF7, PC6, and MKN28.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)