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Merck

C3050

Sigma-Aldrich

Cephalothin Natriumsalz

BioReagent, suitable for cell culture

Synonym(e):

7-(2-Thienylacetamino)-cephalosporansäure Natriumsalz, Cephalotin Natriumsalz

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About This Item

Empirische Formel (Hill-System):
C16H15N2NaO6S2
CAS-Nummer:
Molekulargewicht:
418.42
Beilstein:
4120706
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
51101500
PubChem Substanz-ID:

Produktlinie

BioReagent

Form

powder

Methode(n)

cell culture | mammalian: suitable

Löslichkeit

water: 50 mg/mL, clear, colorless to light yellow

Wirkungsspektrum von Antibiotika

Gram-positive bacteria

Wirkungsweise

cell wall synthesis | interferes

Lagertemp.

2-8°C

SMILES String

[Na+].CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)Cc3cccs3)C2=O)C([O-])=O

InChI

1S/C16H16N2O6S2.Na/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10;/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23);/q;+1/p-1/t12-,15-;/m1./s1

InChIKey

VUFGUVLLDPOSBC-XRZFDKQNSA-M

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Allgemeine Beschreibung

Cephalotin is a first generation cephalosporin antibiotic.
Chemical structure: ß-lactam

Biochem./physiol. Wirkung

Mode of Action: Inhibits cell wall synthesis.
Antimicrobial spectrum: Gram-positive cocci.
Mode of Resistance: Cephalosporinase production.
Mode of Action: Disrupts the synthesis of the peptidoglycan layer of bacterial cell walls.

Antimicrobial spectrum: Effective aginast both Gram-positive and Gram-negative bacteria.

Mode of Resistance: Production of cephalosporinase will inactivate the product.

Sonstige Hinweise

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Piktogramme

Health hazard

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Resp. Sens. 1 - Skin Sens. 1

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Die Dokumentenbibliothek aufrufen

Sarah M Drawz et al.
Biochemistry, 49(2), 329-340 (2009-11-21)
The need to develop beta-lactamase inhibitors against class C cephalosporinases of Gram-negative pathogens represents an urgent clinical priority. To respond to this challenge, five boronic acid derivatives, including a new cefoperazone analogue, were synthesized and tested against the class C
Reply: Protective effect of topical antibiotics in breast augmentation.
Philip K Pfeiffer et al.
Plastic and reconstructive surgery, 131(1), 115e-115e (2012-12-29)
Jung-Whan Chon et al.
Journal of food science, 77(7), M354-M358 (2012-06-08)
A total of 115 desiccated food samples, including agricultural and marine products, were investigated for the presence of Cronobacter. Cronobacter species were characterized with biochemical tests. Antibiotic resistance was assessed with the disk diffusion method, and the molecular subtypes of
Min-Kyung Kang et al.
Dental materials journal, 31(1), 98-105 (2012-01-27)
Dental implant failure often occurs due to oral bacterial infection. The aim of this study was to demonstrate that antibiotic efficacy could be enhanced with modified titanium. First, the titanium was modified by anodization and heat-treatment. Then, a biomimetic coating
Bulent Tokgoz et al.
Renal failure, 32(2), 179-184 (2010-03-05)
Aminoglycosides have been used in the treatment of CAPD peritonitis despite their potential risk for ototoxicity. The ototoxicity risk of intraperitoneally administered aminoglycosides has been investigated by a number of studies. However, their results are somewhat conflicting. The aim of

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