C2105

Z-Val-Ala-Asp fluoromethyl ketone

≥90% (TLC), Caspase-1 inhibitor, powder

• Synonym(e): Z-VAD-FMK, Non-methylated
• Empirische Formel (Hill-System): C₂₁H₂₈FN₃O₇
• CAS-Nummer: 161401-82-7
• Molekulargewicht: 453.46
• UNSPSC Code: 12352209
• PubChem Substance ID: 329774926
• NACRES: NA.77
• MDL number: MFCD03452883
• Assay: ≥90% (TLC)
• Form: powder

Eigenschaften

• Produktname: Z-Val-Ala-Asp fluoromethyl ketone, powder, ≥90% (TLC)
• Quality Segment: 200
• assay: ≥90% (TLC)
• form: powder
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)CF
• InChI: 1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1
• InChI key: SUUHZYLYARUNIA-YEWWUXTCSA-N

Beschreibung

Biochem/physiol Actions

Non-methylated competitive and irreversible inhibitor of caspase-1, as well as other caspases, which can be used directly with purified enzymes. It does not require esterase to hydrolyze the O-methyl ester like the cell-permeable form, Z-Val-Ala-Asp(OMe) fluoromethyl ketone (Product Code V-116).

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)